Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities

MA Ortega, MA Álvarez-Mon, C García-Montero… - Molecular …, 2023 - nature.com
Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

The role of the probiotic Akkermansia muciniphila in brain functions: insights underpinning therapeutic potential

R Xu, Y Zhang, S Chen, Y Zeng, X Fu… - Critical reviews in …, 2023 - Taylor & Francis
The role of Akkermansia muciniphila, one of the most abundant microorganisms of the
intestinal microbiota, has been studied extensively in metabolic diseases, such as obesity …

A role of gut–microbiota–brain axis via subdiaphragmatic vagus nerve in depression-like phenotypes in Chrna7 knock-out mice

Y Yang, A Eguchi, X Wan, L Chang, X Wang… - Progress in Neuro …, 2023 - Elsevier
The α7 subtype of the nicotinic acetylcholine receptor (α7 nAChR: coded by Chrna7) is
known to regulate the cholinergic ascending anti-inflammatory pathway. We previously …

Caspase-1 affects chronic restraint stress-induced depression-like behaviors by modifying GABAergic dysfunction in the hippocampus

M Li, X Sun, Z Wang, Y Li - Translational Psychiatry, 2023 - nature.com
Major depression disorder (MDD) is one of the most common psychiatric disorders and one
of the leading causes of disability in worldwide. Both inflammation and GABAergic …

Bifidobacterium: a probiotic for the prevention and treatment of depression

J Li, J Wang, M Wang, L Zheng, Q Cen… - Frontiers in …, 2023 - frontiersin.org
Depression is a common psychological disease, which has become one of the main factors
affecting human health. It has a serious impact on individuals, families, and society. With the …

Probiotics for the treatment of depression and its comorbidities: A systemic review

J Gao, L Zhao, Y Cheng, W Lei, Y Wang… - Frontiers in Cellular …, 2023 - frontiersin.org
Depression is one of the most common psychiatric conditions, characterized by significant
and persistent depressed mood and diminished interest, and often coexists with various …

Flavonoids from Seabuckthorn (Hippophae rhamnoides L.) restore CUMS-induced depressive disorder and regulate the gut microbiota in mice

CX Xia, AX Gao, Y Zhu, TTX Dong, KWK Tsim - Food & Function, 2023 - pubs.rsc.org
Seabuckthorn (Hippophae rhamnoides L.), which is enriched with flavonoids, including
isorhamnetin, quercetin and kaempferol, is a representative example of “medicine food …

Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a …

E Schneider, JPK Doll, N Schweinfurth… - Journal of Psychiatry and …, 2023 - jpn.ca
Background: In major depressive disorder (MDD), cognitive dysfunctions strongly contribute
to functional impairments but are barely addressed in current therapies. Novel treatment …

Bacillus licheniformis prevents and reduces anxiety-like and depression-like behaviours

S Feng, C Meng, Y Liu, Y Yi, A Liang, Y Zhang… - Applied Microbiology …, 2023 - Springer
As common mental disorders, depression and anxiety impact people all around the world.
Recent studies have found that the gut microbiome plays an important role in mental health …