The role of striatal Cav1. 3 calcium channels in therapeutics for Parkinson's disease

ME Caulfield, FP Manfredsson… - Voltage-gated Ca2+ …, 2023 - Springer
Parkinson's disease (PD) is a relentlessly progressive neurodegenerative disorder with
typical motor symptoms that include rigidity, tremor, and akinesia/bradykinesia, in addition to …

Systems and methods for treating levodopa dyskinesia, enhancing motor benefit, and delaying disease progression

F Manfredsson, K Steece-Collier - US Patent App. 17/998,128, 2023 - Google Patents
Disclosed are systems and compositions for reducing the expression of a CaV1. 3 protein in
a subject and methods of using the systems for treating dyskinesias induced by DA agonist …