Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases
Chemokines belong to the family of cytokines with chemoattractant properties that regulate
chemotaxis and leukocyte migration, as well as the induction of angiogenesis and …
chemotaxis and leukocyte migration, as well as the induction of angiogenesis and …
[HTML][HTML] Cytoprotective remedies for ameliorating nephrotoxicity induced by renal oxidative stress
Aims Nephrotoxicity is the hallmark of anti-neoplastic drug metabolism that causes oxidative
stress. External chemical agents and prescription drugs release copious amounts of free …
stress. External chemical agents and prescription drugs release copious amounts of free …
Nephroprotective effect of AT-MSCs against cisplatin-induced EMT is improved by azilsartan via attenuating oxidative stress and TGF-β/Smad signaling
The nephrotoxicity of cisplatin (CIS) is a significant complication that challenges its clinical
applicability. The epithelial to mesenchymal transition (EMT) may be included in the …
applicability. The epithelial to mesenchymal transition (EMT) may be included in the …
Cisplatin in liver cancer therapy
S Hamaya, K Oura, A Morishita, T Masaki - International Journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary liver tumor and is often
diagnosed at an unresectable advanced stage. Systemic chemotherapy as well as …
diagnosed at an unresectable advanced stage. Systemic chemotherapy as well as …
Ruthenium (II)‐Dithiocarbazates as Anticancer Agents: Synthesis, Solution Behavior, and Mitochondria‐Targeted Apoptotic Cell Death
The reaction of the Ru (PPh3) 3Cl2 with HL1− 3− OH (− OH stands for the oxime hydroxyl
group; HL1− OH= diacetylmonoxime‐S‐benzyldithiocarbazonate; HL2− OH …
group; HL1− OH= diacetylmonoxime‐S‐benzyldithiocarbazonate; HL2− OH …
Biodegradable hydrogel from pectin and carboxymethyl cellulose with Silibinin loading for lung tumor therapy
L Yin, W Duan, Y Chen, D Chen, Y Wang, S Guo… - International Journal of …, 2023 - Elsevier
Serious side effects of chemotherapy drugs greatly limited the anticancer performance, while
targeted drug delivery could improve the therapeutic effect and reduce side effects. In this …
targeted drug delivery could improve the therapeutic effect and reduce side effects. In this …
[HTML][HTML] Biomimetic theranostic nanoparticles for effective anticancer therapy and MRI imaging
Cancer remains a leading cause of mortality worldwide, necessitating the development of
innovative therapeutic approaches. Nanoparticle-based drug delivery systems have …
innovative therapeutic approaches. Nanoparticle-based drug delivery systems have …
Integrated Microarray-Based Data Analysis of miRNA Expression Profiles: Identification of Novel Biomarkers of Cisplatin-Resistance in Testicular Germ Cell Tumours
J Roška, J Lobo, D Ivovič, L Wachsmannová… - International Journal of …, 2023 - mdpi.com
Testicular germ cell tumours (TGCTs) are the most common solid malignancy among young
men, and their incidence is still increasing. Despite good curability with cisplatin (CDDP) …
men, and their incidence is still increasing. Despite good curability with cisplatin (CDDP) …
Highly Sensitive Cyanine Dyes for Rapid Sensing of NAD(P)H in Mitochondria and First-Instar Larvae of Drosophila melanogaster
DL Arachchige, SK Dwivedi, S Jaeger… - ACS Applied Bio …, 2023 - ACS Publications
We have developed two highly sensitive cyanine dyes, which we refer to as probes A and B.
These dyes are capable of quick and sensitive sensing of NAD (P) H. The dyes were …
These dyes are capable of quick and sensitive sensing of NAD (P) H. The dyes were …
α-Hederin Saponin Augments the Chemopreventive Effect of Cisplatin against Ehrlich Tumors and Bioinformatic Approach Identifying the Role of SDF1/CXCR4/p-AKT …
Stromal cell-derived factor-1 (SDF1) and its CXC chemokine receptor type 4 receptor
(CXCR4) are significant mediators for cancer cells' proliferation, and we studied their …
(CXCR4) are significant mediators for cancer cells' proliferation, and we studied their …