The Impact of BDNF, NTRK2, NGFR, CREB1, GSK3B, AKT, MAPK1, MTOR, PTEN, ARC, and SYN1 Genetic Polymorphisms in Antidepressant Treatment …
This study aimed to investigate the influence of genetic variants in neuroplasticity-related
genes on antidepressant treatment phenotypes. The BDNF-TrkB signaling pathway, as well …
genes on antidepressant treatment phenotypes. The BDNF-TrkB signaling pathway, as well …
Differential metabolic alterations in IDH1 mutant vs. wildtype glioma cells promote epileptogenesis through distinctive mechanisms
D McAfee, M Moyer, J Queen, A Mortazavi… - Frontiers in Cellular …, 2023 - frontiersin.org
Glioma-related epilepsy (GRE) is a hallmark clinical presentation of gliomas with significant
impacts on patient quality of life. The current standard of care for seizure management is …
impacts on patient quality of life. The current standard of care for seizure management is …
Depression and suicide
M Boldrini, JJ Mann - Neurobiology of brain disorders, 2023 - Elsevier
This chapter reviews the epidemiology and neurobiology of major depressive disorder and
suicide. Depression and suicide rates in different countries around the world have changed …
suicide. Depression and suicide rates in different countries around the world have changed …
Everolimus attenuates glutamate-induced PC12 cells death
Background Glutamate-induced neuronal cell death plays a key role in neurodegenerative
diseases such as Alzheimer's and Parkinson's diseases. Some recent studies reported the …
diseases such as Alzheimer's and Parkinson's diseases. Some recent studies reported the …
[HTML][HTML] 4-F-PCP, a Novel PCP analog ameliorates the depressive-like behavior of chronic social defeat stress mice via NMDA receptor antagonism
DMD Ortiz, M Kim, HJ Lee, CJ Botanas… - Biomolecules & …, 2023 - ncbi.nlm.nih.gov
Major depressive disorder is a leading cause of disability in more than 280 million people
worldwide. Monoamine-based antidepressants are currently used to treat depression, but …
worldwide. Monoamine-based antidepressants are currently used to treat depression, but …
Activation of the mTOR pathway promotes neurite growth through upregulation of CD44 expression
J Zhang, W Gan, R Peng, L Lu… - Journal of International …, 2023 - journals.sagepub.com
Objective To explore the intrinsic mechanism of the mammalian target of rapamycin (mTOR)
pathway activation and promotion of neuronal axon growth. Methods Human neuroblastoma …
pathway activation and promotion of neuronal axon growth. Methods Human neuroblastoma …
[HTML][HTML] Dopamine D1 and NMDA receptor co-regulation of protein translation in cultured nucleus accumbens neurons
Protein translation is essential for some forms of synaptic plasticity. We used nucleus
accumbens (NAc) medium spiny neurons (MSN), co-cultured with cortical neurons to restore …
accumbens (NAc) medium spiny neurons (MSN), co-cultured with cortical neurons to restore …
LAVENDER ESSENTIAL OIL IMPROVED DEPRESSIVE BEHAVIOR IN MICE AFTER INTERFERON-α ADMINISTRATION BUT NOT AFTER CYCLOSPORINE A …
SE Naeini, A Mesripour… - Bulletin of …, 2023 - bpsa.journals.ekb.eg
The purpose of this study was to assess whether Lavender essential oil (Lav) could alleviate
depressive symptoms induced by Interferon-α (IFN-α) therapy, which reduces tryptophan …
depressive symptoms induced by Interferon-α (IFN-α) therapy, which reduces tryptophan …