Accumulating evidence supports not only the functional role of the gut microbiome in cancer
development and progression but also its role in defining the efficacy and toxicity of …

Probiotics are frequently consumed as functional food and widely used as dietary
supplements, but are also recommended in treating or preventing various gastrointestinal …

Background Irinotecan is a chemotherapeutic agent used to treat a variety of tumors,
including colorectal cancer (CRC). In the intestine, it is transformed into SN-38 by gut …

Cancer cachexia is a multi-organ syndrome with unintentional weight loss, sarcopenia, and
systemic inflammation. Gastrointestinal (GI) cancer patients are more susceptible to …

Oral and intestinal mucositis are debilitating inflammatory diseases observed in cancer
patients undergoing chemo-radiotherapy. These are devastating clinical conditions which …

Despite ongoing breakthroughs in novel anticancer therapies, chemotherapy remains a
mainstream therapeutic modality in different types of cancer. Unfortunately, chemotherapy …

Background The prevalence of breast cancer and its mortality rate are increasing rapidly
among women worldwide. On other hand, the courses of chemotherapy as the main …

Cancer chemotherapy has allowed many patients to survive, but not without risks derived
from its adverse effects. Drugs, such as 5-fluorouracil, irinotecan, oxaliplatin, methotrexate …

Beneficial effects of Lactiplantibacillus plantarum strains have been widely reported.
Knowing that the effects of probiotic bacteria are strain-dependent, this study aimed to …

Cancer therapy is often associated with severe side effects such as drug induced weight
loss, also known as chemotherapy-induced cachexia. The aim of this study was to …