Multiple therapeutic approaches of glioblastoma multiforme: from terminal to therapy
Glioblastoma multiforme (GBM) is an aggressive brain cancer showing poor prognosis.
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …
Phenothiazine derivatives and their impact on the necroptosis and necrosis processes. A review
M Otręba, J Stojko, A Rzepecka-Stojko - Toxicology, 2023 - Elsevier
The current review focuses on the effect of phenothiazine derivatives, tested in vitro, on
necrosis and necroptosis, the latter constitutes one of the kinds of programmed cell death …
necrosis and necroptosis, the latter constitutes one of the kinds of programmed cell death …
A cell type selective YM155 prodrug targets receptor-interacting protein kinase 2 to induce brain cancer cell death
Glioblastoma (GBM) is the most prevalent and aggressive primary central nervous system
(CNS) malignancy. YM155 is a highly potent broad-spectrum anti-cancer drug that was …
(CNS) malignancy. YM155 is a highly potent broad-spectrum anti-cancer drug that was …
A combination of metformin and epigallocatechin gallate potentiates glioma chemotherapy in vivo
Glioma is the most devastating high-grade tumor of the central nervous system, with dismal
prognosis. Existing treatment modality does not provide substantial benefit to patients and …
prognosis. Existing treatment modality does not provide substantial benefit to patients and …
Interactions of Nanoscale Self-Assembled Peptide-Based Assemblies with Glioblastoma Cell Models and Spheroids
CG Lebedenko, ME Murray, BG Goncalves… - ACS …, 2023 - ACS Publications
Peptide nanoassemblies have garnered remarkable importance in the development of novel
nanoscale biomaterials for drug delivery into tumor cells. Taking advantage of receptor …
nanoscale biomaterials for drug delivery into tumor cells. Taking advantage of receptor …
Chlorpromazine affects glioblastoma bioenergetics by interfering with pyruvate kinase M2
C Abbruzzese, S Matteoni, P Matarrese… - Cell Death & …, 2023 - nature.com
Glioblastoma (GBM) is the most frequent and lethal brain tumor, whose therapeutic outcome-
only partially effective with current schemes-places this disease among the unmet medical …
only partially effective with current schemes-places this disease among the unmet medical …
Novel sights on therapeutic, prognostic, and diagnostics aspects of non-coding RNAs in glioblastoma multiforme
JR Mekala, K Adusumilli, S Chamarthy… - Metabolic Brain …, 2023 - Springer
Glioblastoma Multiforme (GBM) is the primary brain tumor and accounts for 200,000 deaths
each year worldwide. The standard therapy includes surgical resection followed by …
each year worldwide. The standard therapy includes surgical resection followed by …
Glioblastoma as a Novel Drug Repositioning Target: Updated State
H Hosseinalizadeh, A Ebrahimi… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Glioblastoma multiforme (GBM) is an aggressive form of adult brain tumor that can arise from
a low-grade astrocytoma. In recent decades, several new conventional therapies have been …
a low-grade astrocytoma. In recent decades, several new conventional therapies have been …
Multilevel Pharmacological Effects of Antipsychotics in Potential Glioblastoma Treatment
Glioblastoma Multiforme (GBM) is a debilitating type of brain cancer with a high mortality
rate. Despite current treatment options such as surgery, radiotherapy, and the use of …
rate. Despite current treatment options such as surgery, radiotherapy, and the use of …
[HTML][HTML] Methylation of RARß is a New Clinical Biomarker for Treatment in Higher-grade Gliomas
Background: The dysregulation of various pathways and cellular processes contributes to
the carcinogenic transition from low-grade gliomas to high-grade gliomas. The altered tumor …
the carcinogenic transition from low-grade gliomas to high-grade gliomas. The altered tumor …