Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles

SM Davidson, CM Boulanger, E Aikawa… - Cardiovascular …, 2023 - academic.oup.com
Extracellular vesicles (EVs) are nanosized vesicles with a lipid bilayer that are released from
cells of the cardiovascular system, and are considered important mediators of intercellular …

Plant-derived exosome-like nanovesicles: current progress and prospects

N Mu, J Li, L Zeng, J You, R Li, A Qin, X Liu… - International Journal …, 2023 - Taylor & Francis
Exosomes are small extracellular vesicles, ranging in size from 30–150nm, which can be
derived from various types of cells. In recent years, mammalian-derived exosomes have …

[HTML][HTML] Lipidomic analysis of adipose-derived extracellular vesicles reveals specific EV lipid sorting informative of the obesity metabolic state

A Blandin, I Dugail, G Hilairet, M Ponnaiah… - Cell reports, 2023 - cell.com
Adipose extracellular vesicles (AdEVs) transport lipids that could participate in the
development of obesity-related metabolic dysfunctions. This study aims to define mouse …

Technological aspects of manufacturing and analytical control of biological nanoparticles

S Brezgin, A Parodi, A Kostyusheva… - Biotechnology …, 2023 - Elsevier
Extracellular vesicles (EVs) are cell-derived biological nanoparticles that gained great
interest for drug delivery. EVs have numerous advantages compared to synthetic …

[HTML][HTML] Bacterial extracellular vesicle applications in cancer immunotherapy

K Suri, A D'Souza, D Huang, A Bhavsar, M Amiji - Bioactive Materials, 2023 - Elsevier
Cancer therapy is undergoing a paradigm shift toward immunotherapy focusing on various
approaches to activate the host immune system. As research to identify appropriate immune …

Nanostructured‐Based Optical Readouts Interfaced with Machine Learning for Identification of Extracellular Vesicles

C del Real Mata, O Jeanne, M Jalali… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are shed from cancer cells into body fluids, enclosing molecular
information about the underlying disease with the potential for being the target cancer …

[HTML][HTML] Endoplasmin is a hypoxia-inducible endoplasmic reticulum-derived cargo of extracellular vesicles released by cardiac cell lines

A Koncz, L Turiák, K Németh, D Lenzinger, T Bárkai… - Membranes, 2023 - mdpi.com
Cardiomyopathies are leading causes of human mortality. Recent data indicate that the
cardiomyocyte-derived extracellular vesicles (EVs) released upon cardiac injury are present …

[HTML][HTML] A novel approach for large-scale manufacturing of small extracellular vesicles from bone marrow-derived mesenchymal stromal cells using a hollow fiber …

V Jakl, M Ehmele, M Winkelmann… - … in Bioengineering and …, 2023 - frontiersin.org
Mesenchymal stromal cells (MSCs) are promising therapeutic candidates in a variety of
diseases due to having immunomodulatory and pro-regenerative properties. In recent years …

[HTML][HTML] Engineered extracellular vesicles as therapeutics of degenerative orthopedic diseases

J Wei, Z Ou, B Tong, Z Liao, C Yang - Frontiers in bioengineering and …, 2023 - frontiersin.org
Degenerative orthopedic diseases, as a global public health problem, have made serious
negative impact on patients' quality of life and socio-economic burden. Traditional …

[HTML][HTML] Polyethylene glycol-based isolation of urinary extracellular vesicles, an easily adoptable protocol

AD Singh, S Patnam, A Manocha, L Bashyam… - MethodsX, 2023 - Elsevier
Urine is a highly advantageous biological specimen for biomarker research and is a non-
invasive source. Most of the urinary biomarkers are non-specific, volatile and need extensive …