Reducing long‐term mortality post transcatheter aortic valve replacement requires systemic differentiation of patient‐specific coronary hemodynamics

S Khodaei, L Garber, M Abdelkhalek… - Journal of the …, 2023 - Am Heart Assoc
Background Despite the proven benefits of transcatheter aortic valve replacement (TAVR)
and its recent expansion toward the whole risk spectrum, coronary artery disease is present …

Predictors of myocardial ischemia in patients with Kawasaki Disease: insights from patient-specific simulations of coronary hemodynamics

K Menon, J Seo, R Fukazawa, S Ogawa… - Journal of …, 2023 - Springer
Current treatments for patients with coronary aneurysms caused by Kawasaki disease (KD)
are based primarily on aneurysm size. This ignores hemodynamic factors influencing …

[HTML][HTML] Impact of TAVR on coronary artery hemodynamics using clinical measurements and image‐based patient‐specific in silico modeling

L Garber, S Khodaei, N Maftoon… - Scientific Reports, 2023 - nature.com
In recent years, transcatheter aortic valve replacement (TAVR) has become the leading
method for treating aortic stenosis. While the procedure has improved dramatically in the …

Vein fate determined by flow-based but time-delayed integration of network architecture

S Marbach, N Ziethen, L Bastin, FK Bäuerle, K Alim - Elife, 2023 - elifesciences.org
Veins in vascular networks, such as in blood vasculature or leaf networks, continuously
reorganize, grow or shrink, to minimize energy dissipation. Flow shear stress on vein walls …

An open loop 0D-3D modeling of pulsatile hemodynamics for the diagnosis of a suspected coronary arterial disease with patient data

S Kumar, BV Kumar, SK Rai, O Shankar - Physics of Fluids, 2023 - pubs.aip.org
Due to the high degree of curvature of the coronary arteries, normal blood flow patterns are
disrupted, making them susceptible sites for stenosis and atherosclerosis, leading to …

[HTML][HTML] Personalized coronary and myocardial blood flow models incorporating CT perfusion imaging and synthetic vascular trees

K Menon, MO Khan, ZA Sexton, J Richter, K Nieman… - medRxiv, 2023 - ncbi.nlm.nih.gov
Computational simulations of coronary artery blood flow, using anatomical models based on
clinical imaging, are an emerging non-invasive tool for personalized treatment planning …

Vascular adaptation model from force balance: Physarum polycephalum as a case study

S Marbach, N Ziethen, K Alim - New Journal of Physics, 2023 - iopscience.iop.org
Understanding vascular adaptation, namely what drives veins to shrink or grow, is key for
the self-organization of flow networks and their optimization. From the top–down principle of …

[HTML][HTML] Transport of nitrite from large arteries modulates regional blood flow during stress and exercise

JC Muskat, CF Babbs, CJ Goergen… - Frontiers in …, 2023 - frontiersin.org
Background Acute cardiovascular stress increases systemic wall shear stress (WSS)–a
frictional force exerted by the flow of blood on vessel walls–which raises plasma nitrite …

[HTML][HTML] A novel method for noninvasive quantification of fractional flow reserve based on the custom function

H Zhang, X Song, R Wu, N Li, Q Hou, J Xie… - … in Bioengineering and …, 2023 - frontiersin.org
Boundary condition settings are key risk factors for the accuracy of noninvasive
quantification of fractional flow reserve (FFR) based on computed tomography angiography …

Abnormal wall shear stress area is correlated to coronary artery bypass graft remodeling 1 year after surgery

N Tran-Nguyen, AT Yan, S Fremes, P Triverio… - Annals of Biomedical …, 2023 - Springer
Coronary artery bypass graft surgery is a common intervention for coronary artery disease;
however, it suffers from graft failure, and the underlying mechanisms are not fully …