Retinal ischemia is involved in the occurrence and development of various eye diseases,
including glaucoma, diabetic retinopathy, and central retinal artery occlusion. To the best of …

The capacity to survive and thrive in conditions of limited resources and high inflammation is
a major driver of tumor malignancy. Here we identified slow-cycling ADAM12+ PDGFRα+ …

Eukaryotic initiation factor 5A2 (eIF5A2) is overexpressed in many types of cancer, and
spermidine-mediated eIF5A hypusination (eIF5Ahpu) appears to be essential to most of …

Polymerase 1 and transcript release factor (PTRF, encoding by Cavin-1) regulates
interleukin 33 (IL-33) release, which is implicated in asthma development. Z-DNA binding …

Background Neutrophil extracellular traps (NETs) can cause acute lung injury (ALI)/acute
respiratory distress syndrome (ARDS) by inducing macrophage pyroptosis. The purpose of …

Aortic aneurysm and dissection (AAD) are leading causes of death in the elderly. Recent
studies have demonstrated that silicate ions can manipulate multiple cells, especially …

Background NEC is a life-threatening gastrointestinal disease in neonates, the
pathogenesis of which remains poorly understood. Methods CCL3 levels in intestinal tissue …

Silicosis is a diffuse fibrotic lung disease in which excessive inflammatory responses are
triggered by silica exposure. Pyroptosis, a pro-inflammatory mode of programmed cell death …

Introduction Brown adipose tissue (BAT) is mainly responsible for mammalian non-shivering
thermogenesis and promotes energy expenditure. Meanwhile, similar to white adipose …

Abstract Ethnopharmacological relevance Wuwei Shexiang Pills (WWSX), a classic Tibetan
medicine, consists of Chebulae Fructus (removed pit), Aucklandiae Radix, Moschus, Aconiti …