Systemic pharmacological treatments for chronic plaque psoriasis: a network meta‐analysis

E Sbidian, A Chaimani, R Guelimi… - Cochrane Database …, 2023 - cochranelibrary.com
Background Psoriasis is an immune‐mediated disease with either skin or joints
manifestations, or both, and it has a major impact on quality of life. Although there is …

[HTML][HTML] Challenges and future trends in the treatment of psoriasis

HJ Lee, M Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Psoriasis is a chronic inflammatory skin disorder, and current treatments include topical
therapies, phototherapy, systemic immune modulators, and biologics, aiming to alleviate …

Disease modification in inflammatory skin disorders: opportunities and challenges

T Bieber - Nature Reviews Drug Discovery, 2023 - nature.com
Progress in understanding of the mechanisms underlying chronic inflammatory skin
disorders, such as atopic dermatitis and psoriasis vulgaris, has led to new treatment options …

Microneedles as a momentous platform for psoriasis therapy and diagnosis: A state-of-the-art review

BHJ Gowda, MG Ahmed, U Hani, P Kesharwani… - International Journal of …, 2023 - Elsevier
Psoriasis is a chronic, autoimmune, and non-communicable skin disease with a worldwide
prevalence rate of 2–3%, creating an economic burden on global health. Some significant …

[HTML][HTML] Heat shock protein 90 inhibitor RGRN-305 potently attenuates skin inflammation

H Ben Abdallah, S Seeler, A Bregnhøj… - Frontiers in …, 2023 - frontiersin.org
Introduction Chronic inflammatory skin diseases may have a profound negative impact on
the quality of life. Current treatment options may be inadequate, offering an unsatisfactory …

Brodalumab in plaque psoriasis: real‐world data on effectiveness, safety and clinical predictive factors of initial response and drug survival over a period of 104 weeks

N Rompoti, M Politou, I Stefanaki… - Journal of the …, 2023 - Wiley Online Library
Background Brodalumab, a fully human IgG2k antibody blocking the receptor of IL17, is
characterized by a rapid onset of action with high skin clearance rates in clinical trials. Since …

Ionic liquids: momentous tools in transdermal delivery of biomacromolecules

L Li, Z Tai, X Wu, J Wu, T Zhang, Z Chen… - Advanced …, 2023 - Wiley Online Library
Transdermal drug delivery is a promising strategy characterized by minor fluctuations in
blood concentrations, few adverse effects, convenience, and excellent patient compliance …

A strategy towards disentangling treatment refractory from misdiagnosed axial Spondyloarthritis

D McGonagle, R Ramonda, L Scagnellato… - Autoimmunity …, 2023 - Elsevier
Axial spondyloarthritis (axSpA) encompasses radiographic axial SpA (r-axSpA), formally
designated as ankylosing spondylitis (AS) and non-radiographic axial SpA (nr-axSpA). The …

[HTML][HTML] A target-based discovery from a parasitic helminth as a novel therapeutic approach for autoimmune diseases

Y Ni, R Xiong, Y Zhu, N Luan, C Yu, K Yang, H Wang… - …, 2023 - thelancet.com
Summary Background Regulatory T cells (Tregs) can alleviate the development of
autoimmune and inflammatory diseases, thereby proposing their role as a new therapeutic …

[HTML][HTML] Pathology and treatment of psoriasis using nanoformulations

D Thirumal, RK Sindhu, S Goyal, A Sehgal, A Kumar… - Biomedicines, 2023 - mdpi.com
Psoriasis (PSO) is an inflammatory skin condition that causes a variety of diseases and
significantly decreases the life characteristics of patients, and substantially diminishes …