The impact of the cellular environment and aging on modeling Alzheimer's disease in 3D cell culture models
M Hebisch, S Klostermeier, K Wolf… - Advanced …, 2023 - Wiley Online Library
Creating a cellular model of Alzheimer's disease (AD) that accurately recapitulates disease
pathology has been a longstanding challenge. Recent studies showed that human AD …
pathology has been a longstanding challenge. Recent studies showed that human AD …
Hydrogels and bioprinting in bone tissue engineering: creating artificial stem‐cell niches for in vitro models
Advances in bioprinting have enabled the fabrication of complex tissue constructs with high
speed and resolution. However, there remains significant structural and biological …
speed and resolution. However, there remains significant structural and biological …
[HTML][HTML] Assessing cell migration in hydrogels: An overview of relevant materials and methods
Cell migration is essential in numerous living processes, including embryonic development,
wound healing, immune responses, and cancer metastasis. From individual cells to …
wound healing, immune responses, and cancer metastasis. From individual cells to …
The applications of 3D printing in wound healing: The external delivery of stem cells and antibiosis
Q Yu, Q Wang, L Zhang, W Deng, X Cao… - Advanced Drug Delivery …, 2023 - Elsevier
As the global number of chronic wound patients rises, the financial burden and social
pressure on patients increase daily. Stem cells have emerged as promising tissue …
pressure on patients increase daily. Stem cells have emerged as promising tissue …
Extracellular matrix drives tumor organoids toward desmoplastic matrix deposition and mesenchymal transition
Patient-derived tumor organoids have been established as promising tools for in vitro
modelling of multiple tumors, including cholangiocarcinoma (CCA). However, organoids are …
modelling of multiple tumors, including cholangiocarcinoma (CCA). However, organoids are …
A combination of matrix stiffness and degradability dictate microvascular network assembly and remodeling in cell-laden poly (ethylene glycol) hydrogels
The formation of functional capillary blood vessels that can sustain the metabolic demands
of transplanted parenchymal cells remains one of the biggest challenges to the clinical …
of transplanted parenchymal cells remains one of the biggest challenges to the clinical …
The relationship of rheological properties and the performance of silk fibroin hydrogels in tissue engineering application
J Elango, A Lijnev, C Zamora-Ledezma, F Alexis… - Process …, 2023 - Elsevier
Hydrogel-based systems are widely used for conventional 3D-cell culture, where cells can
be seeded on or embedded in 3D-matrix gels for cultivation. Several new approaches have …
be seeded on or embedded in 3D-matrix gels for cultivation. Several new approaches have …
[HTML][HTML] Tumor decellularization reveals proteomic and mechanical characteristics of the extracellular matrix of primary liver cancer
Tumor initiation and progression are critically dependent on interaction of cancer cells with
their cellular and extracellular microenvironment. Alterations in the composition, integrity …
their cellular and extracellular microenvironment. Alterations in the composition, integrity …
Modified ECM-based bioink for 3D printing of multi-scale vascular networks
The survival and function of tissues depend on appropriate vascularization. Blood vessels of
the tissues supply oxygen, and nutrients and remove waste and byproducts. Incorporating …
the tissues supply oxygen, and nutrients and remove waste and byproducts. Incorporating …
Sandwich Culture Platforms to Investigate the Roles of Stiffness Gradients and Cell–Matrix Adhesions in Cancer Cell Migration
Simple Summary Metastasis is the primary cause of death in cancer patients, yet there is a
shortage of highly potent anti-metastatic drugs. Screening for anti-metastatic compounds …
shortage of highly potent anti-metastatic drugs. Screening for anti-metastatic compounds …