One of the most common chronic complications arising from diabetes is diabetic peripheral
neuropathy. Depending on research statistics, approximately half of the people who have …

Neuroimaging is a powerful tool to investigate potential associations between chronic pain
and brain structure. However, the proliferation of studies across diverse chronic pain …

Multiple molecular pathways including the receptor for advanced glycation end-products-
diaphanous related formin 1 (RAGE-Diaph1) signaling are known to play a role in diabetic …

OBJECTIVE Despite increasing evidence demonstrating structural and functional alterations
within the central nervous system in diabetic peripheral neuropathy (DPN), the …

Type 2 diabetes mellitus (T2DM) is closely linked to cognitive decline and alterations in
brain structure and function. Resting-state functional magnetic resonance imaging (rs-fMRI) …

Introduction In this study, we used proton Magnetic Resonance Spectroscopy (1H-MRS) to
determine the neuronal function in the thalamus and primary somatosensory (S1) cortex in …

Diabetes disrupts the corticospinal tract (CST) system components that control hindlimb and
trunk movement, resulting in weakness of the lower extremities. However, there is no …

Postpartum depression (PPD) is the most common postpartum psychiatric disorder, which
can negatively affect both mothers and their offspring. Although the functional changes of …

People with diabetes are at increased risk of developing painful diabetic neuropathy.
Current guidelines that are aimed at symptom control achieved meaningful pain relief in only …

Central and Peripheral Neurodegeneration in Diabetes Mellitus and Peripheral Neuropathies
Page 1 1 Central and Peripheral Neurodegeneration in Diabetes Mellitus and Peripheral …