ncRNA-mediated fatty acid metabolism reprogramming in HCC

K Xu, P Xia, X Chen, W Ma, Y Yuan - Trends in Endocrinology & Metabolism, 2023 - cell.com
The challenges of hepatocellular carcinoma (HCC) pathogenesis, diagnosis, treatment, and
prognosis evaluation are obvious. Hepatocyte-specific fatty acid (FA) metabolic …

[HTML][HTML] PRC2 mediated KLF2 down regulation: a therapeutic and diagnostic axis during tumor progression

N Taghehchian, A Maharati, I Akhlaghipour… - Cancer Cell …, 2023 - Springer
Surgery and chemo-radiotherapy are used as the common first-line treatment options in
many cancers. However, tumor relapse is observed in many cancer patients following such …

Upregulation of Superenhancer‐driven LncRNA FASRL by USF1 promotes de novo fatty acid biosynthesis to exacerbate hepatocellular carcinoma

JY Peng, DK Cai, RL Zeng, CY Zhang, GC Li… - Advanced …, 2023 - Wiley Online Library
Superenhancers drive abnormal gene expression in tumors and promote malignancy.
However, the relationship between superenhancer‐associated long noncoding RNA …

[HTML][HTML] LncTUG1 promotes hepatocellular carcinoma immune evasion via upregulating PD-L1 expression

R Wu, W Liu, Q Yang, J Zhang, P Hou, J Xiong, L Wu… - Scientific Reports, 2023 - nature.com
HCC is one of the most common malignant tumors worldwide. Although traditional treatment
methods have been improved in recent years, the survival rate of HCC patients has not been …

[HTML][HTML] Long noncoding RNA study: Genome-wide approaches

S Tao, Y Hou, L Diao, Y Hu, W Xu, S Xie, Z Xiao - Genes & diseases, 2023 - Elsevier
Long noncoding RNAs (lncRNAs) have been confirmed to play a crucial role in various
biological processes across several species. Though many efforts have been devoted to the …

[HTML][HTML] LINC00853 contributes to tumor stemness of gastric cancer through FOXP3-mediated transcription of PDZK1IP1

X Hu, M Zhao, S Hu, Q Liu, W Liao, L Wan… - Biological Procedures …, 2023 - Springer
Background The incidence and mortality of gastric cancer (GC) are high worldwide. Tumor
stemness is a major contributor to tumorigenesis and development of GC, in which long non …

lncRNA TUG1 as potential novel biomarker for prognosis of cardiovascular diseases

H Haybar, NS Sadati, D Purrahman… - …, 2023 - Taylor & Francis
Globally, cardiovascular diseases (CVDs) are among the leading causes of death. In light of
the high prevalence and mortality of CVDs, it is imperative to understand the molecules …

[HTML][HTML] Long noncoding RNA TUG1 promotes malignant progression of osteosarcoma by enhancing ZBTB7C expression

X An, W Wu, P Wang, A Mahmut, J Guo, J Dong… - Biomedical Journal, 2023 - Elsevier
Background Dysregulation of long non-coding RNAs (lncRNAs) is an important component
of tumorigenesis. Aberrant expression of lncRNA taurine upregulated gene 1 (lncTUG1) has …

[HTML][HTML] Interplay of LncRNA TUG1 and TGF-β/P53 expression in colorectal cancer

BA Ibrahim, MA Gobran, AEM Metwalli… - Asian Pacific Journal …, 2023 - ncbi.nlm.nih.gov
Background: Colorectal cancer (CRC) is one of the most prevalent and deadly cancers
worldwide. It is still necessary to further define the mechanisms and explore the therapeutic …

[HTML][HTML] LncRNA SNHG20 silencing inhibits hepatocellular carcinoma progression by sponging miR-5095 from MBD1

B Xu, C Li, B Yang, F Zhou, K Tang… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Objective: Long non-coding RNAs (lncRNAs) may have a significant regulatory effect on the
progression of hepatocellular carcinoma (HCC), according to recent data. This study aims to …