DNMT1 inhibition by pUG-fold quadruplex RNA

LI Jansson-Fritzberg, CI Sousa, MJ Smallegan… - RNA, 2023 - rnajournal.cshlp.org
Aberrant DNA methylation is one of the earliest hallmarks of cancer. DNMT1 is responsible
for methylating newly replicated DNA, but the precise regulation of DNMT1 to ensure faithful …

Longitudinal conditional probability of symmetric DNA methylation in Arabidopsis plants

H Fernandes - bioRxiv, 2023 - biorxiv.org
DNA replication in high eukaryotes requires the faithful transmission of both the sequence
and its methylation status. DNA methyltransferases are not consistently reliable enzymes for …

Epigenetics and Chronic Diseases, Role of Functional Foods in Preventing Tumorigenesis

K Pourvali, G Shimi, A Shakery… - Molecular Mechanisms of …, 2023 - api.taylorfrancis.com
“Epigenetic” was first coined by Conrad Waddington, a developmental biologist, and is
defined as the inheritance of acquired traits induced by environmental stimulants. As a …

Investigation of DNA methylation turnover in pluripotency and early differentiation

L Haut - 2023 - refubium.fu-berlin.de
Throughout embryonic development, cells undergo a series of lineage decisions,
accompanied by morphological and functional changes, culminating in the formation of a …

Novel Long non-coding RNA MAGEA6-DT1 Promotes Expression of the Melanoma Antigen Family 6 by Demethylating its Enhancer

J Hao, Y Wang, W Liu, W Yuan, J Jia, S Li, H Yang… - 2023 - researchsquare.com
Background The occurrence and progression of various solid tumors are associated with the
melanoma-associated antigen A (MAGE-A) family. Although it was demonstrated that …

An investigation of the mechanisms underlying the developmental origins of health and disease and their impact on telomeres

R Maganga - 2023 - research-repository.uwa.edu.au
Unfavourable developmental environments are believed to" program" offspring to metabolic
disease. In this thesis, the effects of dietary programming on telomere length were examined …

[PDF][PDF] DNA methylation: classification, similarities and differences, and the importance of inactive homologues of DNA (cytosine-5) methyltransferases in higher …

H Fernandes - osf.io
DNA methylation is an evolutionarily conserved epigenetic mark used for genomic stability
and gene expression regulation that is known to rely on active and inactive homologues of …