Molecular docking, synthesis and evaluation of the antimicrobial, antiproliferative, and antioxidant properties of β-lactam bisindoles

S Ranjbari, A Jarrahpour, S Kianpour, S Sepehri… - Journal of Molecular …, 2023 - Elsevier
A series of novel bis (indolyl) methane-β-lactam hybrids has been efficiently synthesized by
a [2+ 2]-cycloaddition reaction of imines 5a-c with ketenes derived from substituted acetic …

Discovery of anticancer agents with c-Met inhibitory potential by virtual and experimental screening of a chemical library

M Mortazavi, E Raufi, T Damghani… - European journal of …, 2023 - Elsevier
Abstract c-Met receptor tyrosine kinase has recently emerged as an important target with
therapeutic implications in pancreatic cancer. In this study, we carried out a docking virtual …

Acenaphthotriazine Thio-triazole Derivatives as Anti-cancer Agents Triggering Cell Cycle Arrest in Breast Cancer Cells

A Iraji, N Shahrokh, O Firuzi… - Letters in Drug …, 2023 - ingentaconnect.com
Background: Cancer is one of the most devastating diseases, affecting the lives of millions of
people around the world. Introduction: A series of acenaphtho [1, 2-e][1, 2, 4] triazine …