Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …

Sphingolipids play an important role in the development of diabetes, both type 1 and type 2
diabetes, as well as in the development of both micro-and macro-vascular complications …

Asthma is a complex heterogeneous disease caused by gene–environment interactions.
Although numerous genome-wide association studies have been conducted, these …

Background Genome-wide association studies have identified several risk alleles for early
childhood asthma, particularly in the 17q21 locus and in the cadherin-related family member …

Juvenile idiopathic arthritis (JIA) is an autoimmune, inflammatory joint disease with complex
genetic etiology. Previous GWAS have found many genetic loci associated with JIA …

Background Environmental, genetic, and microbial factors are independently associated
with childhood asthma. Objective We sought to determine the roles of environmental …

This article provides an overview of the findings obtained from the Vitamin D Antenatal
Asthma Reduction Trial (VDAART) spanning a period of 15 years. The review covers various …

Though asthma is a common and relatively easy to diagnose disease, attempts at primary or
secondary prevention, and cure, have been disappointing. The widespread use of inhaled …

Genome‐wide association studies have linked the ORM (yeast)–like protein isoform 3
(ORMDL3) to asthma severity. Although ORMDL3 is a member of a family that negatively …

Deciphering cell-type-specific 3D structures of chromatin is challenging. Here, we present
InferLoop, a novel method for inferring the strength of chromatin interaction using single-cell …