Most of the leading causes of death, such as cardiovascular diseases, cancer, dementia,
neurodegenerative diseases, and many more, are associated with sterile inflammation …

Human diseases are characterized by the perpetuation of an inflammatory condition in
which the levels of Reactive Oxygen Species (ROS) are quite high. Excessive ROS …

Systemic inflammation triggers protective as well as pro-inflammatory responses in the brain
based on neuronal and/or cytokine signaling, and it associates with acutely and protractedly …

Globally, inflammation and metabolic disorders pose serious public health problems and are
major health concerns. It has been shown that natural polyphenols are effective in the …

Abstract Hesperidin (C 28 H 34 O 15), a flavanone glycoside abundantly present in citrus
fruits, has proven therapeutic effects including anti-inflammatory activities. Herein, we report …

The NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome is a
multiprotein complex and component of the innate immune system that is activated by …

The hypoxia-inducing factor (HIF) is a central transcription factor in cellular oxygen sensing
and regulation. It is common that the inflammation always appears in many diseases, like …

Objective An increase in the number of neutrophils (NEUs) has long been associated with
infections in the knee joints; however, their impact on knee osteoarthritis (KOA) …

Cardiac hypertrophy is the main adaptive response of the heart to chronic loads; however,
prolonged or excessive hypertrophy promotes myocardial interstitial fibrosis, systolic …

In diseases like cardiovascular diseases, diabetes, asthma, and cancer, inflammation play a
very important role. Diet influences various phases of inflammation and, in turn, has a great …