[HTML][HTML] Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against …
F Poggialini, C Vagaggini, A Brai, C Pasqualini… - Pharmaceutics, 2023 - mdpi.com
The therapeutic use of tyrosine kinase inhibitors (TKIs) represents one of the successful
strategies for the treatment of glioblastoma (GBM). Pyrazolo [3, 4-d] pyrimidines have …
strategies for the treatment of glioblastoma (GBM). Pyrazolo [3, 4-d] pyrimidines have …
Chemical and Biological Versatility of Pyrazolo[3,4-d]Pyrimidines: One Scaffold, Multiple Modes of Action
A Trentini, S Hanau, MC Manfrinato… - Future Medicinal …, 2023 - Taylor & Francis
Plain language summary Pyrazolo [3, 4-d] pyrimidines are chemical compounds possessing
remarkable versatility and significance in both biological and chemical contexts. These …
remarkable versatility and significance in both biological and chemical contexts. These …
[HTML][HTML] Some novel peptides containing a modified pyrazolopyrimidine moiety: design, synthesis, and in vitro antibacterial screening
AR Al-Mohammadi, MG Zayda, MG Zayda… - Applied Biological …, 2023 - Springer
Numerous peptide drugs are currently undergoing advanced phases of clinical testing to
determine their efficacy in combating antibiotic-resistant bacterial pathogens. Our aim was to …
determine their efficacy in combating antibiotic-resistant bacterial pathogens. Our aim was to …