Akkermansia muciniphila: from its critical role in human health to strategies for promoting its abundance in human gut microbiome

S Ghaffari, A Abbasi, MH Somi… - Critical reviews in …, 2023 - Taylor & Francis
Akkermansia muciniphila, a frequent colonizer in the gut mucous layer of individuals, has
constantly been recognized as a promising candidate for the next generation of probiotics …

[HTML][HTML] Akkermansia muciniphila in neuropsychiatric disorders: friend or foe?

W Lei, Y Cheng, J Gao, X Liu, L Shao… - Frontiers in cellular …, 2023 - ncbi.nlm.nih.gov
An accumulating body of evidence suggests that the bacterium Akkermansia muciniphila
exhibits positive systemic effects on host health, mainly by improving immunological and …

Akkermansia muciniphila exacerbates food allergy in fibre-deprived mice

A Parrish, M Boudaud, ET Grant, S Willieme… - Nature …, 2023 - nature.com
Alterations in the gut microbiome, including diet-driven changes, are linked to the rising
prevalence of food allergy. However, little is known about how specific gut bacteria trigger …

Akkermansia muciniphila as a Next-Generation Probiotic in Modulating Human Metabolic Homeostasis and Disease Progression: A Role Mediated by Gut–Liver …

H Jian, Y Liu, X Wang, X Dong, X Zou - International Journal of Molecular …, 2023 - mdpi.com
Appreciation of the importance of Akkermansia muciniphila is growing, and it is becoming
increasingly relevant to identify preventive and/or therapeutic solutions targeting gut–liver …

Akkermansia muciniphila and its membrane protein ameliorates intestinal inflammatory stress and promotes epithelial wound healing via CREBH and miR-143/145

H Wade, K Pan, Q Duan, S Kaluzny, E Pandey… - Journal of Biomedical …, 2023 - Springer
Background The intestinal epithelial barrier is the interface for interaction between gut
microbiota and host metabolic systems. Akkermansia muciniphila (A. muciniphila) is a key …

[PDF][PDF] High-fat-diet-associated intestinal microbiota exacerbates psoriasis-like inflammation by enhancing systemic γδ T cell IL-17 production

K Sonomoto, R Song, D Eriksson, AM Hahn, X Meng… - Cell Reports, 2023 - cell.com
Although it is known that psoriasis is strongly associated with obesity, the mechanistic
connection between diet and skin lesions is not well established. Herein, we showed that …

[HTML][HTML] The effect of probiotics on immune responses and their therapeutic application: a new treatment option for multiple sclerosis

B Hashemi, M Abdollahi, S Abbaspour-Aghdam… - Biomedicine & …, 2023 - Elsevier
Multiple sclerosis (MS) is known as a chronic inflammatory disease (CID) that affects the
central nervous system and leads to nerve demyelination. However, the exact cause of MS …

[HTML][HTML] A diet enriched in omega-3 PUFA and inulin prevents type 1 diabetes by restoring gut barrier integrity and immune homeostasis in NOD mice

M Lo Conte, M Antonini Cencicchio… - Frontiers in …, 2023 - frontiersin.org
Introduction The integrity of the gut barrier (GB) is fundamental to regulate the crosstalk
between the microbiota and the immune system and to prevent inflammation and …

Akkermansia muciniphila - friend or foe in colorectal cancer?

EO Gubernatorova, EA Gorshkova… - Frontiers in …, 2023 - frontiersin.org
Akkermansia muciniphila is a gram-negative anaerobic bacterium, which represents a part
of the commensal human microbiota. Decline in the abundance of A. muciniphila among …

Feeding the gut microbiome: impact on multiple sclerosis

M Bronzini, A Maglione, R Rosso, M Matta… - Frontiers in …, 2023 - frontiersin.org
Multiple sclerosis (MS) is a multifactorial neurological disease characterized by chronic
inflammation and immune-driven demyelination of the central nervous system (CNS). The …