In addition to carrying and transmitting genetic material, some DNA molecules have specific
binding ability or catalytic function. DNA with this special function is collectively referred to as …

In the past few years, with the in-depth research of functional nucleic acids and isothermal
amplification techniques, their applications in the field of biosensing have attracted great …

Nucleic acid nanomaterials with good biocompatibility, biodegradability, and
programmability have important applications in biomedical field. Nucleic acid nanomaterials …

Liquid biopsy is a technology that exhibits potential to detect cancer early, monitor therapies,
and predict cancer prognosis due to its unique characteristics, including noninvasive …

The reaction kinetics and yield of traditional DNA assembly with a low local concentration in
homogeneous solution remain challenging. Exploring confined catalytic DNA assembly …

Integrating clinical rare cell enrichment, culture, and single-cell phenotypic profiling is
currently hampered by the lack of competent technologies, which typically suffer from weak …

Efficient capture of circulating tumor cells (CTCs) from cancer patients is an important
technique that may promote early diagnosis and prognosis monitoring of cancer. However …

Circulating tumor cells (CTCs) offer rich information for early disease diagnosis and therapy
evaluation. However, the limited sensitivity, binding affinity, and stability of current …

We develop a multivalent aptamer meshed open pore membrane with a signal amplification
method as a simple and robust platform for sensitive, robust, and high-flux detection of E …

Background: Nucleic acid is a genetic material that shows great potential in a variety of
biological applications. With the help of nanotechnology, the fabrication of DNA-based …