Economic value of knowing BRCA status: BRCA testing for prostate cancer prevention and optimal treatment

M Oh, A McBride, S Bhattacharjee, M Slack… - Expert Review of …, 2023 - Taylor & Francis
Background We aimed to estimate the incremental lifetime effects, costs, and net-monetary-
benefit (NMB) of knowing BRCA information by testing of patients with low-risk localized …

Prediction of upgrade to clinically significant prostate cancer in patients under active surveillance: Performance of a fully automated AI‐algorithm for lesion detection …

B Oerther, H Engel, A Nedelcu, CL Schlett… - The …, 2023 - Wiley Online Library
Abstract Background Multiparametric MRI (mpMRI) improves the detection of aggressive
prostate cancer (PCa) subtypes. As cases of active surveillance (AS) increase and tumor …

The role of multiparametric magnetic resonance in active surveillance of a low‐risk prostate cancer cohort from clinical practice

L Chamorro Castillo, L García Morales… - The …, 2023 - Wiley Online Library
Introduction Active surveillance (AS) is considered a suitable management practice for those
patients with low‐risk prostate cancer (PCa). At present, however, the role of multiparametric …

Optimizing active surveillance for prostate cancer using partially observable Markov decision processes

W Li, BT Denton, TM Morgan - European Journal of Operational Research, 2023 - Elsevier
We describe a finite-horizon partially observable Markov decision process (POMDP)
approach to optimize decisions about whether and when to perform biopsies for patients on …

Expanding the role of PSMA PET in active surveillance

A Jain, AJ Nassour, T Dean, I Patterson, L Tarlinton… - BMC urology, 2023 - Springer
Introduction Accurate grading at the time of diagnosis is fundamental to risk stratification and
treatment decision making, particularly for men being considered for Active Surveillance …

Les grands principes des traitements du cancer de prostate localisé

J Le Guévelou, A Peyrottes, L Meynard, E Barret… - Médecine Nucléaire, 2023 - Elsevier
Résumé Le cancer de la prostate (CaP) représentait en 2020 le deuxième cancer en termes
de fréquence chez l'homme après le cancer bronchopulmonaire, et la 5 e cause de décès …

Active surveillance should be considered for select men with Grade Group 2 prostate cancer

KR Pekala, O Bergengren, JA Eastham, SV Carlsson - BMC urology, 2023 - Springer
Background Treatment decisions for localized prostate cancer must balance patient
preferences, oncologic risk, and preservation of sexual, urinary and bowel function. While …

Clinical and histological predictive factors of reclassification of prostate cancer patients on active surveillance

GA Carratalà, CG Perelló, BA Barroso, AS Llopis… - Actas Urológicas …, 2023 - Elsevier
Introduction and objective Active surveillance (AS) has been established as a therapeutic
strategy in patients with low-risk prostate cancer. Demographic and anatomopathological …

[HTML][HTML] Building Blocks of Prostate Cancer Diagnostics

K Sandeman - 2023 - helda.helsinki.fi
The most prevalent cancer in men is prostate cancer (PCa). Diagnostic methods currently
detect most PCa at an early stage, but the diagnosis of many PCa cases that are clinically …

Development of a novel signature integrating clinical, imaging and epigenetic information to tailor pelvic nodal treatment in prostate cancer

M Bandini - 2023 - iris.unisr.it
La prostatectomia radicale (RP) è un'opzione di trattamento negli gli uomini con carcinoma
prostatico localizzato. In questi pazienti si consiglia di eseguire la linfoadenectomia pelvica …