Among the complications of diabetes, cardiovascular events and cardiac insufficiency are
considered two of the most important causes of death. Experimental and clinical evidence …

The public health issue of glucolipid metabolic disorders (GLMD) has grown significantly,
posing a grave threat to human wellness. Its prevalence is rising yearly and tends to affect …

Ischemia–reperfusion (I/R) injury is a disease process that affects several vital organs. There
is widespread agreement that the NLRP3 inflammasome pathway plays a crucial role in the …

Biofilm‐infected diabetic wounds (BIDWs) with hyperglycemia and bacterial colonization are
characterized by disordered inflammation and abnormal activation of NLRP3 …

Retinal ischemia/reperfusion (I/R) injury is a common pathological process responsible for
cellular damage in glaucoma, diabetic retinopathy and hypertensive retinopathy. Metformin …

The nucleotide-binding domain-like receptor protein 3 (NLRP3) inflammasome in the kidney
and the heart is increasingly being suggested to play a key role in mediating inflammation …

Aim To examine the protective effect of vitamin B12 against myocardial ischemia/reperfusion
(I/R) injury and elucidate its underlying mechanism of action. Methods Mice were subjected …

The current study intended to delve into the mechanisms of dexmedetomidine (Dex) in
regulating myocardial pyroptosis against myocardial ischemia/reperfusion injury (MIRI). The …

Myocardial remodeling refers to structural and functional disorders of the heart caused by
molecular biological changes in the cardiac myocytes in response to neurological and …

Ferroptosis is a novel type of regulated cell death (RCD) discovered in recent years, where
abnormal intracellular iron accumulation leads to the onset of lipid peroxidation, which …