Body fluid-derived stem cells—an untapped stem cell source in genitourinary regeneration

RL Huang, Q Li, JX Ma, A Atala, Y Zhang - Nature Reviews Urology, 2023 - nature.com
Somatic stem cells have been obtained from solid organs and tissues, including the bone
marrow, placenta, corneal stroma, periosteum, adipose tissue, dental pulp and skeletal …

[HTML][HTML] Cell-based therapy for urethral regeneration: a narrative review and future perspectives

Y Jin, W Zhao, M Yang, W Fang, G Gao, Y Wang, Q Fu - biomedicines, 2023 - mdpi.com
Urethral stricture is a common urological disease that seriously affects quality of life.
Urethroplasty with grafts is the primary treatment, but the autografts used in clinical practice …

[HTML][HTML] Precision nephrotoxicity testing using 3D in vitro models

P Yu, H Zhu, CC Bosholm, D Beiner, Z Duan… - Cell & Bioscience, 2023 - Springer
Nephrotoxicity is a significant concern during the development of new drugs or when
assessing the safety of chemicals in consumer products. Traditional methods for testing …

Genome engineering of human urine-derived stem cells to express lactoferrin and deoxyribonuclease

Z Kenigsberg, RC Welch, J Bejoy… - … Engineering Part A, 2023 - liebertpub.com
Urine-derived stem cells (USCs) are adult kidney cells that have been isolated from a urine
sample and propagated in tissue culture on gelatin-coated plates. Urine is a practical and …

[HTML][HTML] Urine-derived stem cells in neurological diseases: current state-of-the-art and future directions

C Cavaleiro, GJM Afonso, PJ Oliveira… - Frontiers in Molecular …, 2023 - frontiersin.org
Stem cells have potential applications in the field of neurological diseases, as they allow for
the development of new biological models. These models can improve our understanding of …

[HTML][HTML] Tissue engineering in reconstructive urology—The current status and critical insights to set future directions-critical review

K Ławkowska, C Rosenbaum, P Petrasz… - … in Bioengineering and …, 2023 - frontiersin.org
Advanced techniques of reconstructive urology are gradually reaching their limits in terms of
their ability to restore urinary tract function and patients' quality of life. A tissue engineering …

Infection responsive coatings to reduce biofilm formation and encrustation of urinary catheters

AJ Slate, OE Clarke, M Kerio… - Journal of applied …, 2023 - academic.oup.com
Aims The care of patients undergoing long-term urethral catheterization is frequently
complicated by Proteus mirabilis infection. This organism forms dense, crystalline biofilms …

[HTML][HTML] In vivo safety and biodistribution profile of Klotho-enhanced human urine-derived stem cells for clinical application

SH Kim, SH Lee, JA Jin, HJ So, JU Lee, MJ Ji… - Stem Cell Research & …, 2023 - Springer
Background Urine-derived stem cells (UDSCs) can be easily isolated from urine and
possess excellent stem cell characteristics, making them a promising source for cell …

Efek Simvastatin terhadap Urin dan Jaringan Buli-Buli pada Tikus Model Sistitis Interstisial Akut yang Diinduksi Protamin Sulfat

ADI Hasanuddin, R Minhajat… - Alami Journal …, 2023 - journal3.uin-alauddin.ac.id
The pathophysiology of interstitial cystitis (IC) is complicated and related to statin drug use
without any established underlying mechanisms. This study used a rat model of acute IC …

Exosome-mediated renal protection: Halting the progression of fibrosis

C Liu, Q Li, JX Ma, B Lu, T Criswell, Y Zhang - Genes & Diseases, 2023 - Elsevier
Renal fibrosis is a complex and multifactorial process that involves inflammation, cell
proliferation, collagen, and fibronectin deposition in the kidney, ultimately leading to chronic …