Myofibroblasts are the construction workers of wound healing and repair damaged tissues
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …

The kidneys play a key role in maintaining total body homeostasis. The complexity of this
task is reflected in the unique architecture of the organ. Ureteral obstruction greatly affects …

Fibrosis, a process caused by excessive deposition of extracellular matrix (ECM), is a
common cause and outcome of organ failure and even death. Researchers have made …

Fibrosis is a pathological tissue repair activity in which many myofibroblasts are activated
and extracellular matrix are excessively accumulated, leading to the formation of permanent …

Cardiac fibrosis constitutes irreversible necrosis of the heart muscle as a consequence of
different acute (myocardial infarction) or chronic (diabetes, hypertension,…) diseases but …

Fibrosis is the end-stage pathological manifestation of many chronic diseases. Infiltration of
inflammatory cells and activation of myofibroblasts are the most prominent features of …

Fibrosis is a common process of tissue repair response to multiple injuries in all chronic
progressive diseases, which features with excessive deposition of extracellular matrix …

Gas6 (growth arrest-specific gene 6) is a widely expressed vitamin K-dependent protein that
is involved in many biological processes such as homeostatic regulation, inflammation and …

Fibrosis results from excess extracellular matrix accumulation, which alters normal tissue
architecture and impedes function. In the salivary gland, fibrosis can be induced by …

Liver fibrosis is a reversible pathological process and a wound healing response to liver
injury. As an early stage of various liver diseases, liver fibrosis can develop into cirrhosis …