Nucleobase modifications are prevalent in eukaryotic mRNA and their discovery has
resulted in the emergence of epitranscriptomics as a research field. The most abundant …

The coleoid cephalopods have the largest brains, and display the most complex behaviors,
of all invertebrates. The molecular and cellular mechanisms that underlie these remarkable …

Physiological homeostasis becomes compromised during ageing, as a result of impairment
of cellular processes, including transcription and RNA splicing,,–. However, the molecular …

Background RNA editing at the Q/R site of GluA2 occurs with~ 99% efficiency in the healthy
brain, so that the majority of AMPARs contain GluA2 (R) instead of the exonically encoded …

Background RNA editing is a process that increases transcriptome diversity, often through
Adenosine Deaminases Acting on RNA (ADARs) that catalyze the deamination of …

Extensive adenosine-to-inosine (A-to-I) editing of nuclear-transcribed mRNAs is the
hallmark of metazoan transcriptional regulation. Here, by profiling the RNA editomes of 22 …

MicroTom has a short growth cycle and high transformation efficiency, and is a prospective
model plant for studying organ development, metabolism, and plant–microbe interactions …

RNA editing is among the most common RNA level modifications for generating amino acid
changes. We identified a COPA A-to-I RNA editing event in CRC metastasis. Our results …

Epitranscriptomics refers to post-transcriptional regulation of gene expression via RNA
modifications and editing that affect RNA functions. Many kinds of modifications of mRNA …

Adenosine-to-inosine RNA editing is essential to prevent undesired immune activation. This
diverse process alters the genetic content of the RNA and may recode proteins, change …