The existence of long‐lived IgE antibody‐secreting cells (ASC) is contentious, with the
maintenance of sensitization by the continuous differentiation of short‐lived IgE+ ASC a …

The adaptive immune system has evolved to allow effective responses against a virtually
unlimited number of invading pathogens. This process requires the transient formation of …

Diffuse large B cell lymphoma (DLBCL) often develops resistance and/or relapses in
response to immunochemotherapy. Epigenetic modifiers are frequently mutated in DLBCL …

Cancers often overexpress multiple clinically relevant oncogenes, but it is not known if
combinations of oncogenes in cellular subpopulations within a cancer influence clinical …

Background The clinical and genetic heterogeneity of diffuse large B-cell lymphoma
(DLBCL) presents distinct challenges in predicting response to therapy and overall …

Gut-associated lymphoid tissue (GALT) is organised lymphoid tissue that is chronically
activated by the intestinal microbiota. It generates the IgA response that is critical for …

Antibody responses serve a fundamental role in the clearance of active infections and the
establishment of immunity post-infection or vaccination. Following either infection or …

IL-38 is the latest discovered cytokine of the IL-1 family and has been added to the IL-36
subfamily. Since its discovery in 2001, increasing evidence suggests predominantly anti …

Over 90% of children diagnosed with B-cell non-Hodgkin lymphoma (B-NHL) respond well
to front-line therapy. However, survival for patients with primary refractory or relapsed …

A febre amarela é uma doença infecciosa que continua representando um problema de
saúde pública no Brasil. No ano de 2018 foram confirmados 504 casos silvestres em …