Desorption electrospray ionization mass spectrometry imaging in discovery and development of novel therapies
T Soudah, A Zoabi, K Margulis - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Desorption electrospray ionization mass spectrometry imaging (DESI‐MSI) is one of the
least specimen destructive ambient ionization mass spectrometry tissue imaging methods. It …
least specimen destructive ambient ionization mass spectrometry tissue imaging methods. It …
The development and application of matrix assisted laser desorption electrospray ionization: The teenage years
M Caleb Bagley, KP Garrard… - Mass Spectrometry …, 2023 - Wiley Online Library
In the past 15 years, ambient ionization techniques have witnessed a significant incursion
into the field of mass spectrometry imaging, demonstrating their ability to provide …
into the field of mass spectrometry imaging, demonstrating their ability to provide …
[HTML][HTML] Targeted desorption electrospray ionization mass spectrometry imaging for drug distribution, toxicity, and tissue classification studies
With increased use of mass spectrometry imaging (MSI) in support of pharmaceutical
research and development, there are opportunities to develop analytical pipelines that …
research and development, there are opportunities to develop analytical pipelines that …
Advances in mass spectrometry imaging for toxicological analysis and safety evaluation of pharmaceuticals
Y Chen, Y Xie, L Li, Z Wang… - Mass Spectrometry …, 2023 - Wiley Online Library
Safety issues caused by pharmaceuticals have frequently occurred worldwide, posing a
tremendous threat to human health. As an essential part of drug development, the …
tremendous threat to human health. As an essential part of drug development, the …
Detection of Distinct Distributions of Acetaminophen and Acetaminophen-Cysteine in Kidneys up to 10 μm Resolution and Identification of a Novel Acetaminophen …
MA Mamun, MM Rahman, T Sakamoto… - Journal of the …, 2023 - ACS Publications
Drug distribution studies in tissue are crucial for understanding the pharmacokinetics and
potential toxicity of drugs. Recently, matrix-assisted laser desorption ionization-mass …
potential toxicity of drugs. Recently, matrix-assisted laser desorption ionization-mass …
DESI-MSI-based technique to unravel spatial distribution of COMT inhibitor Tolcapone
J Rebouta, ML Dória, F Campos, F Araújo… - International Journal of …, 2023 - Elsevier
Ascertaining compound exposure and its spatial distribution are essential steps in the drug
development process. Desorption electrospray ionization mass spectrometry (DESI-MSI) is a …
development process. Desorption electrospray ionization mass spectrometry (DESI-MSI) is a …