[HTML][HTML] Longitudinal spatial mapping of lipid metabolites reveals pre-symptomatic changes in the hippocampi of Huntington's disease transgenic mice

F Farzana, MJ McConville, T Renoir, S Li, S Nie… - Neurobiology of …, 2023 - Elsevier
In Huntington's disease (HD), a key pathological feature includes the development of
inclusion-bodies of fragments of the mutant huntingtin protein in the neurons of the striatum …

Lipid biosynthesis perturbation impairs endoplasmic reticulum–associated degradation

SM Turk, CJ Indovina, JM Miller, DL Overton… - Journal of Biological …, 2023 - ASBMB
The relationship between lipid homeostasis and protein homeostasis (proteostasis) is
complex and remains incompletely understood. We conducted a screen for genes required …

Fatty acids as a direct regulator of aldosterone hypersecretion

G Ling, J Bruno, SG Albert, S Dhindsa - Molecular and Cellular …, 2023 - Elsevier
Primary hyperaldosteronism is a major cause of secondary hypertension and carries
additional cardiovascular risks beyond that of the elevated blood pressure. Primary …

Linagliptin and secoisolariciresinol diglucoside attenuate hyperlipidemia and cardiac hypertrophy induced by a high-methionine diet in rats via suppression of …

IA Jalal, A Elkhoely, SK Mohamed… - Frontiers in …, 2023 - frontiersin.org
Background: Cardiac hypertrophy (CH) is one of the contributing causes of morbidity and
mortality. Hyperhomocysteinemia (HHcy) is one of the diseases which may predispose …

The frequency of fatty liver in patients with alopecia areata: A case–control study

Z Tehranchinia, F Abdollahimajd… - Journal of Cosmetic …, 2023 - Wiley Online Library
Background Alopecia areata (AA) is an immune‐mediated nonscarring hair loss disorder
with multiple subtypes, including alopecia universalis (AU). Previous studies have shown a …

Hyperhomocysteinemia: its impact on cardiovascular disease and atherosclerosis

IA Jalal, A Elkhoely, SK Mohamed… - Bulletin of …, 2023 - bpsa.journals.ekb.eg
Hyperhomocysteinemia (HHcy) was found to be a risk factor for cardiovascular disorders
and many other diseases. HHcy occurs when homocysteine (Hcy) exceeds 15 μmol/L. The …

[PDF][PDF] The role of hepatic SURF4 in the lipid metabolism and the development of atherosclerosis

Y Shen - 2023 - era.library.ualberta.ca
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of morbidity and
mortality worldwide. Long-term elevated plasma levels of low-density lipoprotein cholesterol …