[HTML][HTML] Atorvastatin liposomes in a 3D-printed polymer film: a repurposing approach for local treatment of oral candidiasis

EM Nour, SE El-Habashy, MG Shehat… - Drug Delivery and …, 2023 - Springer
Oral candidiasis (OC) is an opportunistic fungal infection, common amongst the elderly and
the immunocompromised. Unfortunately, the therapeutic efficacy of common antifungals is …

Chitosan-based buccal mucoadhesive patches to enhance the systemic bioavailability of tizanidine

MD Arpa, NÜ Okur, MK Gök, S Özgümüş… - International Journal of …, 2023 - Elsevier
Tizanidine hydrochloride (TZN) is a muscle relaxant used to treat a variety of disorders such
as painful muscle spasms and chronic spasticity. TZN has low oral bioavailability due to …

Novel benzydamine hydrochloride and chlorhexidine gluconate loaded bioadhesive films for local treatment of buccal infections

MD Arpa, AP Yağcılar, SN Biltekin - Journal of Drug Delivery Science and …, 2023 - Elsevier
Benzydamine hydrochloride (BZD), chlorhexidine gluconate (CHG) or their combination are
frequently used as liquid dosage forms for the local treatment of buccal fungal and bacterial …

[HTML][HTML] In Vitro and In Vivo Characterisation of a Mucoadhesive Buccal Film Loaded with Doxycycline Hyclate for Topical Application in Periodontitis

E Dinte, DM Muntean, V Andrei, BA Boșca… - Pharmaceutics, 2023 - mdpi.com
Mucoadhesive films loaded with doxycycline hyclate (Doxy Hyc), consisting of mixtures of
hydroxypropylmethyl cellulose (HPMC) E3, K4 and polyacrylic acid (Carbopol 940), were …

[HTML][HTML] Cydonia oblonga-Seed-Mucilage-Based pH-Sensitive Graft Copolymer for Controlled Drug Delivery—In Vitro and In Vivo Evaluation

M Sarfraz, UR Tulain, A Erum, NS Malik, A Mahmood… - Pharmaceutics, 2023 - mdpi.com
The primary objective of this study was to assess the potential utility of quince seed mucilage
as an excipient within a graft copolymer for the development of an oral-controlled drug …

Development of denture-fitting, palate-mucoadhesive miconazole nitrate films for denture stomatitis

BA Abou-Taleb, IF Elzoheiry, GS Kotry… - Journal of Drug Delivery …, 2023 - Elsevier
Denture stomatitis commonly affects denture users. Most available antifungal buccal
formulations cannot maintain adequate drug levels in the mouth cavity for a sufficient time …

[HTML][HTML] Determination of Mucoadhesion of Polyvinyl Alcohol Films to Human Intestinal Tissue

L Müller, C Rosenbaum, A Rump, M Grimm, F Klammt… - Pharmaceutics, 2023 - mdpi.com
The absorption of drugs with narrow absorption windows in the upper small intestine can be
improved with a mucoadhesive drug delivery system such as enteric films. To predict the …

[HTML][HTML] Formulation Options for Mucoadhesive Dosage Forms for Use in the Oral Cavity

V Šimunková, E Tichý, M Špaglová… - European Pharmaceutical … - sciendo.com
Mucoadhesive dosage forms, which are used for topical application in the oral cavity, are
currently a very intensively developing field in pharmaceutical technology. Considering the …