[HTML][HTML] From plant to chemistry: Sources of active opioid antinociceptive principles for medicinal chemistry and drug design

R Turnaturi, S Piana, S Spoto, G Costanzo, L Reina… - Molecules, 2023 - mdpi.com
Pain continues to be an enormous global health challenge, with millions of new untreated or
inadequately treated patients reported annually. With respect to current clinical applications …

[PDF][PDF] Use of Dexmedetomidine in Cardiothoracic and Vascular Anesthesia

J Vallés-Torres, T PhDn, AP PhDn, M Iglesias - academia.edu
Dexmedetomidine is a highly selective α2-adrenergic agonist with analgesic and sedative
properties. In the United States, the Food and Drug Administration approved the use of the …

Evaluation of 30-days stability of morphine hydrochloride and clonidine at high and low concentrations in polypropylene syringes

E Catry, ML Colsoul, M Closset, C Nyssen… - European Journal of …, 2023 - ejhp.bmj.com
Objectives Clonidine is an alpha-2 adrenoreceptor agonist and is frequently combined with
opioids (ie, morphine hydrochloride (HCl)) for the management of chronic pain. In palliative …