Free radical as a double-edged sword in disease: Deriving strategic opportunities for nanotherapeutics

L Zhu, M Luo, Y Zhang, F Fang, M Li, F An… - Coordination chemistry …, 2023 - Elsevier
Free radicals, usually containing one or more unpaired electrons, are extremely unstable
and highly reactive with other biological molecules. Recently, there has been increasing …

[HTML][HTML] Application of biomedical materials in the diagnosis and treatment of myocardial infarction

J Zhang, Y Guo, Y Bai, Y Wei - Journal of nanobiotechnology, 2023 - Springer
Myocardial infarction (MI) is a cardiovascular emergency and the leading cause of death
worldwide. Inflammatory and immune responses are initiated immediately after MI, leading …

[HTML][HTML] A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury

Z Li, T Zhao, J Ding, H Gu, Q Wang, Y Wang, D Zhang… - Bioactive materials, 2023 - Elsevier
Spinal cord injury (SCI) is an overwhelming and incurable disabling event accompanied by
complicated inflammation-related pathological processes, such as excessive reactive …

[HTML][HTML] Wet adhesive hydrogel cardiac patch loaded with anti-oxidative, autophagy-regulating molecule capsules and MSCs for restoring infarcted myocardium

T Wu, X Zhang, Y Liu, C Cui, Y Sun, W Liu - Bioactive Materials, 2023 - Elsevier
Hydrogel patch-based stem cell transplantation and microenvironment-regulating drug
delivery strategy is promising for the treatment of myocardial infarction (MI). However, the …

Dopamine‐Based High‐Transparent Hydrogel as Bioadhesive for Sutureless Ocular Tissue Repair

Y Qian, K Xu, L Shen, M Dai, Z Zhao… - Advanced Functional …, 2023 - Wiley Online Library
Ocular injuries and their complications represent the most common causes of visual
impairment. For ocular surgery, there is an unmet need for highly transparent bioadhesives …

Injectable decellularized extracellular matrix hydrogel containing stromal cell-derived factor 1 promotes transplanted cardiomyocyte engraftment and functional …

K Wu, Y Wang, H Yang, Y Chen, K Lu… - … Applied Materials & …, 2023 - ACS Publications
Transplantation of exogenous cardiomyocytes (CMs) is a hopeful method to treat myocardial
infarction (MI). However, its clinical application still remains challenging due to low retention …

Simplified α2-macroglobulin as a TNF-α inhibitor for inflammation alleviation in osteoarthritis and myocardial infarction therapy

W Zheng, T Zhou, Y Zhang, J Ding, J Xie, S Wang… - Biomaterials, 2023 - Elsevier
Tumor necrosis factor α (TNF-α) is a leading proinflammatory cytokine as the master
regulator of inflammation in chronic inflammation diseases. Although TNF-α antagonists …

Injectable polyaniline nanorods/alginate hydrogel with AAV9-mediated VEGF overexpression for myocardial infarction treatment

C Wu, Y Zhang, Y Xu, L Long, X Hu, J Zhang, Y Wang - Biomaterials, 2023 - Elsevier
Intramyocardial injection of hydrogels possesses great potential in the minimally invasive
treatment of myocardial infarction (MI), but the current injectable hydrogels lack conductivity …

3D printable, injectable amyloid-based composite hydrogel of bovine serum albumin and aloe vera for rapid diabetic wound healing

K Naik, P Singh, M Yadav, SK Srivastava… - Journal of Materials …, 2023 - pubs.rsc.org
Protein-based biomaterials, particularly amyloids, have sparked considerable scientific
interest in recent years due to their exceptional mechanical strength, excellent …

In vivo self-assembled shape-memory polyurethane for minimally invasive delivery and therapy

S Li, H Zhang, J Xie, Z Wang, K Wang, Z Zhai… - Materials …, 2023 - pubs.rsc.org
Advanced elastomers are highly in demand for the fabrication of medical devices for
minimally invasive surgery (MIS). Herein, a shape memory and self-healing polyurethane …