Multifunctional hydrogels based on chitosan, hyaluronic acid and other biological macromolecules for the treatment of inflammatory bowel disease: A review
Y Ouyang, J Zhao, S Wang - International journal of biological …, 2023 - Elsevier
Hydrogel is a three-dimensional network polymer material rich in water. It is widely used in
the biomedical field because of its unique physical and chemical properties and good …
the biomedical field because of its unique physical and chemical properties and good …
[HTML][HTML] Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: From mechanism to therapy
J Liu, X Han, T Zhang, K Tian, Z Li, F Luo - Journal of Hematology & …, 2023 - Springer
Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation
of inflammatory responses is associated with most human diseases. Reactive oxygen …
of inflammatory responses is associated with most human diseases. Reactive oxygen …
Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis
F Cao, L Jin, Y Gao, Y Ding, H Wen, Z Qian… - Nature …, 2023 - nature.com
Inflammatory bowel disease can be caused by the dysfunction of the intestinal mucosal
barrier and dysregulation of gut microbiota. Traditional treatments use drugs to manage …
barrier and dysregulation of gut microbiota. Traditional treatments use drugs to manage …
Extracellular vesicles‐derived hybrid nanoplatforms for amplified CD47 blockade‐based cancer immunotherapy
L Tang, Y Yin, Y Cao, C Fu, H Liu, J Feng… - Advanced …, 2023 - Wiley Online Library
Immunomodulation of tumor‐associated macrophages (TAMs) into tumor‐inhibiting M1‐like
phenotype is a promising but challenging strategy. Cleverly, tumor cells overexpress CD47 …
phenotype is a promising but challenging strategy. Cleverly, tumor cells overexpress CD47 …
Probiotic‐inspired nanomedicine restores intestinal homeostasis in colitis by regulating redox balance, immune responses, and the Gut Microbiome
Microbiota‐based therapeutics offer innovative strategies to treat inflammatory bowel
diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the …
diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the …
Oral hydrogel microbeads-mediated in situ synthesis of selenoproteins for regulating intestinal immunity and microbiota
Selenoprotein plays a crucial role in immune cells and inflammatory regulation. However, as
a protein drug that is easily denatured or degraded in the acidic environment of the stomach …
a protein drug that is easily denatured or degraded in the acidic environment of the stomach …
An orally-administered nanotherapeutics with carbon monoxide supplying for inflammatory bowel disease therapy by scavenging oxidative stress and restoring gut …
X Zhang, Z Yuan, J Wu, Y He, G Lu, D Zhang, Y Zhao… - ACS …, 2023 - ACS Publications
Traditional drug-based treatments for inflammatory bowel disease (IBD) have significant
limitations due to their potential off-target systemic side-effects. Currently, there is a lack of …
limitations due to their potential off-target systemic side-effects. Currently, there is a lack of …
[HTML][HTML] A nanoadjuvant that dynamically coordinates innate immune stimuli activation enhances cancer immunotherapy and reduces immune cell exhaustion
SM Jin, YJ Yoo, HS Shin, S Kim, SN Lee… - Nature …, 2023 - nature.com
Although conventional innate immune stimuli contribute to immune activation, they induce
exhausted immune cells, resulting in suboptimal cancer immunotherapy. Here we suggest a …
exhausted immune cells, resulting in suboptimal cancer immunotherapy. Here we suggest a …
[HTML][HTML] The role of Akkermansia muciniphila in inflammatory bowel disease: Current knowledge and perspectives
M Zheng, R Han, Y Yuan, Y Xing, W Zhang… - Frontiers in …, 2023 - frontiersin.org
Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, is a chronic
relapsing gastrointestinal inflammatory disease mediated by dysregulated immune …
relapsing gastrointestinal inflammatory disease mediated by dysregulated immune …
Reactive Oxygen Species‐Activated CO Versatile Nanomedicine with Innate Gut Immune and Microbiome Remodeling Effects for Treating Inflammatory Bowel …
Y Zeng, M Fan, Q Zhou, D Chen, T Jin… - Advanced Functional …, 2023 - Wiley Online Library
Abnormal activation of the gut mucosal immune system and a highly dysregulated gut
microbiota play essential roles in the progression of inflammatory bowel disease (IBD). The …
microbiota play essential roles in the progression of inflammatory bowel disease (IBD). The …