SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice

C Willekens, L Laplane, T Dagher, C Benlabiod… - Leukemia, 2023 - nature.com
Heterozygous mutation targeting proline 95 in Serine/Arginine-rich Splicing Factor 2
(SRSF2) is associated with V617F mutation in Janus Activated Kinase 2 (JAK2) in some …

Constitutive activation of gp130 in T cells results in senescence and premature aging

P Rafii, F Reusswig, J Werner, H Xu… - The Journal of …, 2023 - journals.aai.org
IL-6 family members contribute to host defense through the stimulation of acute-phase
signaling, hematopoiesis, immune reactions, and regenerative processes. To investigate …

SARS-CoV-2 Lysate Stimulation Impairs the Release of Platelet-like Particles and Megakaryopoiesis in the MEG-01 Cell Line

V Lopardo, F Montella, RM Esposito… - International journal of …, 2023 - mdpi.com
SARS-CoV-2 infection causes a considerable inflammatory response coupled with impaired
platelet reactivity, which can lead to platelet disorders recognized as negative prognostic …