[HTML][HTML] Molecular diagnostics in the evaluation of thyroid nodules: Current use and prospective opportunities

J Patel, J Klopper, EE Cottrill - Frontiers in endocrinology, 2023 - frontiersin.org
Thyroid cancer is the most common endocrine malignancy with an estimated 43,800 new
cases to be diagnosed in 2022 and representing the 7th most common cancer in women …

Real-world performance of the Afirma Genomic Sequencing Classifier (GSC)—a meta-analysis

CE Nasr, M Andrioli, M Endo, RM Harrell… - The Journal of …, 2023 - academic.oup.com
Abstract Context The Afirma® GSC aids in risk stratifying indeterminate thyroid nodule
cytology (ITN). The 2018 GSC validation study (VS) reported a sensitivity (SN) of 91 …

Clinical use of molecular data in thyroid nodules and cancer

AS Alzahrani - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Over the past 3 decades, advances in the molecular genetics of thyroid cancer (TC) have
been translated into diagnostic tests, prognostic markers, and therapeutic agents. The main …

Molecular testing in thyroid cancer diagnosis and management

JA Sipos, MD Ringel - Best Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
Molecular diagnostic testing has had a profound impact on the diagnosis and management
of thyroid nodules and thyroid cancer. Based on the tremendous expansion of knowledge of …

[HTML][HTML] Preoperative evaluation of thyroid nodules—diagnosis and management strategies

TD Antonia, LI Maria, GG Ancuta-Augustina - Pathology-Research and …, 2023 - Elsevier
Thyroid cancer is the most common endocrine malignancy, with increasing incidence over
the past few decades. Fine needle aspiration (FNA) biopsy is the gold standard for …

ThyroidPrint®: clinical utility for indeterminate thyroid cytology

R Olmos, JM Domínguez… - Endocrine-Related …, 2023 - erc.bioscientifica.com
Molecular testing contributes to improving the diagnosis of indeterminate thyroid nodules
(ITNs). ThyroidPrint® is a ten-gene classifier aimed to rule out malignancy in ITN. Post …

Molecular testing in fine‐needle aspiration of thyroid nodules

V McMurtry, S Canberk… - Diagnostic Cytopathology, 2023 - Wiley Online Library
Background Thyroid nodules are commonly faced by clinicians as palpable nodules or
incidentally identified on imaging. Nodules that are found to be suspicious by imaging can …

Risk stratification of cytologically indeterminate thyroid nodules with nondiagnostic or benign cytology on repeat FNA: implications for molecular testing and …

EA Hall, P Hartzband, PA VanderLaan… - Cancer …, 2023 - Wiley Online Library
Background Evidence guiding the management of cytologically indeterminate thyroid
nodules with nondiagnostic (ND) or benign cytology on repeat fine‐needle aspiration (FNA) …

Molecular testing for indeterminate thyroid nodules: past, present, and future

R Raghunathan, SS Praw, M Livhits - Current Opinion in …, 2023 - journals.lww.com
Molecular testing of indeterminate thyroid nodules has helped to reduce the burden of
diagnostic surgery, associated healthcare costs, and potential complications. Current …

Advances in molecular profiling and their potential influence on the extent of surgery in well-differentiated thyroid carcinoma (WDTC)

C Parpounas, V Constantinides - Life, 2023 - mdpi.com
Thyroid cancer surgery has evolved dramatically with advances in our understanding of the
biological behaviour of WDTC. Molecular profiling is shedding light on the subset that may …