Inflammation is an essential immune response that helps fight infections and heal tissues.
However, chronic inflammation has been linked to several diseases, including cancer …

Colorectal cancer is a prevalent malignant tumor with a complex and diverse pathogenesis.
In recent years, natural products have shown promising application prospects as sources of …

We conducted a meta‐analysis to evaluate the clinical efficacy of berberine (BBR) in treating
acute ischemic stroke (AIS), explore its anti‐inflammatory effects, and assess its potential …

The Janus kinase/signal transducer and activator of transcription (JAK/STAT) is an intricate
signaling cascade composed of various cytokines, interferons (IFN, growth factors, and other …

Objective Increasing evidence suggests that inflammation appears to play a role in the
genesis of depression. Berberine has potent anti-inflammatory effects and potential …

Nuclear factor (NF)-κB plays a pivotal role in the regulation of inflammatory response in
macrophages. Berberine (BBR), which is an active constituent isolated from Coptis rhizome …

Autophagy is a highly conserved process that maintains cell stability in eukaryotes,
participates in the turnover of intracellular substances to maintain cell function, helps to …

Ethnopharmacological relevance Helicobacter pylori (H. pylori) infection is a frequent
chronic infection. Persistent infection is the strongest risk factor for developing gastric …

As a life-threatening disorder, sepsis-associated lung injury is a dysregulated inflammatory
response to microbial infection, characterized by the infiltration of inflammatory cells into …

Background Tumour-derived small extracellular vesicles (sEVs) play a crucial role in cancer
immunomodulation. In addition to tumour immune microenvironment, the peripheral immune …