[HTML][HTML] Metabolic landscape in cardiac aging: insights into molecular biology and therapeutic implications
S Xie, SC Xu, W Deng, Q Tang - Signal transduction and targeted …, 2023 - nature.com
Cardiac aging is evident by a reduction in function which subsequently contributes to heart
failure. The metabolic microenvironment has been identified as a hallmark of malignancy …
failure. The metabolic microenvironment has been identified as a hallmark of malignancy …
Maternal-fetal cross-talk via the placenta: influence on offspring development and metabolism
Compelling epidemiological and animal experimental data demonstrate that
cardiometabolic and neuropsychiatric diseases originate in a suboptimal intrauterine …
cardiometabolic and neuropsychiatric diseases originate in a suboptimal intrauterine …
[HTML][HTML] Made in the womb: maternal programming of offspring cardiovascular function by an obesogenic womb
Obesity incidence has been increasing at an alarming rate, especially in women of
reproductive age. It is estimated that 50% of pregnancies occur in overweight or obese …
reproductive age. It is estimated that 50% of pregnancies occur in overweight or obese …
[HTML][HTML] Modulation of fetoplacental growth, development and reproductive function by endocrine disrupters
S Basak, S Varma, AK Duttaroy - Frontiers in Endocrinology, 2023 - frontiersin.org
Maternal endocrine homeostasis is vital to a successful pregnancy, regulated by several
hormones such as human chorionic gonadotropin, estrogen, leptin, glucocorticoid, insulin …
hormones such as human chorionic gonadotropin, estrogen, leptin, glucocorticoid, insulin …
[HTML][HTML] Mouse models of preeclampsia with preexisting comorbidities
CA Waker, AE Hwang, S Bowman-Gibson… - Frontiers in …, 2023 - frontiersin.org
Preeclampsia is a pregnancy-specific condition and a leading cause of maternal and fetal
morbidity and mortality. It is thought to occur due to abnormal placental development or …
morbidity and mortality. It is thought to occur due to abnormal placental development or …
[PDF][PDF] Made in the Womb: Maternal Programming of Offspring Cardiovascular Function by an Obesogenic Womb. Metabolites 2023, 13, 845
Obesity incidence has been increasing at an alarming rate, especially in women of
reproductive age. It is estimated that 50% of pregnancies occur in overweight or obese …
reproductive age. It is estimated that 50% of pregnancies occur in overweight or obese …
Maternal obesity attenuates PPARγ nuclear migration impairing offspring adipogenesis
É de Sousa, AC Rodrigues - Journal of Molecular …, 2023 - jme.bioscientifica.com
Maternal obesity predisposes offspring to obesity in adulthood. Since the perinatal period is
a critical window for adipose organogenesis, we evaluated if maternal obesity affects the …
a critical window for adipose organogenesis, we evaluated if maternal obesity affects the …
[HTML][HTML] Maternal obesity-related placental dysfunction: From peri-conception to late gestation
Obesity is a global epidemic with alarmingly high prevalence rates worldwide. The
increasing incidence of obesity among reproductive age women, which progresses to …
increasing incidence of obesity among reproductive age women, which progresses to …
Insulin like growth factor 1 (IGF-1) and IGF binding proteins in obese pregnant women and their babies: Potential effects on placental function and fetal growth
Introduction: The placenta expresses significant amounts of insulin and IGF1 receptors at
distinct locations on both fetal and maternal surfaces. This makes the IGF1 and the insulin …
distinct locations on both fetal and maternal surfaces. This makes the IGF1 and the insulin …