Bacillus subtilis, a swiss army knife in science and biotechnology

J Stülke, A Grüppen, M Bramkamp… - Journal of …, 2023 - Am Soc Microbiol
ABSTRACT Next to Escherichia coli, Bacillus subtilis is the most studied and best
understood organism that also serves as a model for many important pathogens. Due to its …

Improving the nutritional quality of pulses via germination

L Avezum, E Rondet, C Mestres, N Achir… - Food Reviews …, 2023 - Taylor & Francis
Germination is a traditional process and a re-emerging trend in healthy foods, resulting a
progressively increase in scientific research on their nutritional traits and phytochemical …

Metabolic engineering of thermophilic Bacillus methanolicus for riboflavin overproduction from methanol

VJ Klein, LF Brito, F Perez‐Garcia… - Microbial …, 2023 - Wiley Online Library
The growing need of next generation feedstocks for biotechnology spurs an intensification of
research on the utilization of methanol as carbon and energy source for biotechnological …

75 Years of Vitamin A Production: A Historical and Scientific Overview of the Development of New Methodologies in Chemistry, Formulation, and Biotechnology

W Bonrath, B Gao, P Houston… - … Process Research & …, 2023 - ACS Publications
In 1948, the first kilograms of synthetic vitamin A (acetate) were produced by F. Hoffmann-La
Roche, eliminating the need to extract this vital compound from natural sources; this year …

Metabolic Engineering of Bacillus subtilis for Riboflavin Production: A Review

Y Liu, Q Zhang, X Qi, H Gao, M Wang, H Guan, B Yu - Microorganisms, 2023 - mdpi.com
Riboflavin (vitamin B2) is one of the essential vitamins that the human body needs to
maintain normal metabolism. Its biosynthesis has become one of the successful models for …

Biomaterial composed of chitosan, riboflavin, and hydroxyapatite for bone tissue regeneration

J Gaweł, J Milan, J Żebrowski, D Płoch, I Stefaniuk… - Scientific Reports, 2023 - nature.com
Biomaterial engineering approaches involve using a combination of miscellaneous
bioactive molecules which may promote cell proliferation and, thus, form a scaffold with the …

Route selection and reaction engineering for sustainable metabolite synthesis

R Wohlgemuth - Reaction Chemistry & Engineering, 2023 - pubs.rsc.org
The great advances in information technology, machine learning and artificial intelligence
are providing fast access to potential routes to a desired metabolite from possible starting …

Fabrication of multifunctional bio-macromolecule organic-inorganic hybrid system for protein silk: Photochromic, UV protection, fire-proof and super durability

WJ Jin, Y Xin, JP Guan, XW Cheng, MK Zhu… - International Journal of …, 2023 - Elsevier
Nowadays, high value-added and multifunctional textiles have attracted widespread
attention due to the changing demands of modern life. This study focused on the fabrication …

Involvement of a flavoprotein, acetohydroxyacid synthase, in growth and riboflavin production in riboflavin-overproducing Ashbya gossypii mutant

T Kato, M Kano, A Yokomori, J Azegami… - Microbial cell …, 2023 - Springer
Background Previously, we isolated a riboflavin-overproducing Ashbya gossypii mutant (MT
strain) and discovered some mutations in genes encoding flavoproteins. Here, we analyzed …

Enhancing the biosynthesis of riboflavin in the recombinant Escherichia coli BL21 strain by metabolic engineering

B Fu, J Ying, Q Chen, Q Zhang, J Lu, Z Zhu… - Frontiers in …, 2023 - frontiersin.org
In this study, to construct the riboflavin-producing strain R1, five key genes, ribA, ribB, ribC,
ribD, and ribE, were cloned and ligated to generate the plasmid pET-AE, which was …