Regulatory T cell and macrophage crosstalk in acute lung injury: future perspectives

T Guan, X Zhou, W Zhou, H Lin - Cell death discovery, 2023 - nature.com
Acute lung injury (ALI) describes the injury to endothelial cells in the lungs and associated
vessels due to various factors. Furthermore, ALI accompanied by inflammation and …

Animal models of acute exacerbation of pulmonary fibrosis

X Ye, M Zhang, H Gu, M Liu, Y Zhao, Y Shi, S Wu… - Respiratory …, 2023 - Springer
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive scarring interstitial lung disease
with an unknown cause. Some patients may experience acute exacerbations (AE), which …

[HTML][HTML] Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway

Y Zhu, Q Han, L Wang, B Wang, J Chen, B Cai… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Acute lung injury (ALI) is one of the fatal complications of
respiratory virus infections such as influenza virus and coronavirus, which has high clinical …

Schisandrin B protects against LPS-induced inflammatory lung injury by targeting MyD88

W Zhu, W Luo, J Han, Q Zhang, L Ji, AV Samorodov… - Phytomedicine, 2023 - Elsevier
Background Acute lung injury (ALI) is a challenging clinical syndrome that manifests as an
acute inflammatory response. Schisandrin B (Sch B), a bioactive lignan from Schisandra …

Shiwei Qingwen decoction regulates TLR4/NF-κB signaling pathway and NLRP3 inflammasome to reduce inflammatory response in lipopolysaccharide-induced …

Q Zhang, C Yang, S Ma, S Guo, X Hu, Z Zhou… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Shiwei Qingwen decoction (SWQ), a Chinese
herbal formula based on the classic traditional Chinese medicine prescription Yu Ping Feng …

Discovery of 4-oxo-N-phenyl-1, 4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis

J Yang, M Wang, Y Xu, J Liao, X Li, Y Zhou… - European Journal of …, 2023 - Elsevier
Acute lung injury (ALI) and sepsis, characterized by systemic inflammatory response
syndrome, remain the major causes of death in severe patients. Inhibiting the release of …

Macrophage-derived exosomal TNF-α promotes pulmonary surfactant protein expression in PM2. 5-induced acute lung injury

X Hu, J Su, M Chen, Y Tu, C Wu, X Cao, X Yuan… - Science of The Total …, 2023 - Elsevier
Short-term high-concentration exposure to airborne fine particulate matter (PM 2.5) is
strongly associated with the risk of acute lung injury (ALI). It has been recently reported that …

rFGF4 alleviates lipopolysaccharide-induced acute lung injury by inhibiting the TLR4/NF-κB signaling pathway

X Wang, L Zhou, S Ye, S Liu, L Chen, Z Cheng… - International …, 2023 - Elsevier
Acute lung injury (ALI) is a serious and common clinical disease. Despite significant
progress in ALI treatment, the morbidity and mortality rates remain high. However, no …

Irigenin attenuates lipopolysaccharide-induced acute lung injury by inactivating the mitogen-activated protein kinase (MAPK) signaling pathway

D Liu, Q Wang, W Yuan… - Human & Experimental …, 2023 - journals.sagepub.com
Acute lung injury (ALI) is a serious pulmonary inflammation disease with high mortality.
Irigenin, an isoflavone from rhizomes of the Belamcanda chinensis, has been reported to …

CNP-miR146a Decreases Inflammation in Murine Acute Infectious Lung Injury

AE Vaughn, T Lehmann, C Sul, AM Wallbank, BD Lyttle… - Pharmaceutics, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) has approximately 40% in-hospital mortality,
and treatment is limited to supportive care. Pneumonia is the underlying etiology in many …