[HTML][HTML] Pathogenesis of allergic diseases and implications for therapeutic interventions
J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …
Targeting interleukin-33 and thymic stromal lymphopoietin pathways for novel pulmonary therapeutics in asthma and COPD
AA Calderon, C Dimond, DF Choy… - European …, 2023 - Eur Respiratory Soc
Interleukin-33 (IL-33) and thymic stromal lymphopoietin (TSLP) are alarmins that are
released upon airway epithelial injury from insults such as viruses and cigarette smoke, and …
released upon airway epithelial injury from insults such as viruses and cigarette smoke, and …
Laundry detergents and surfactants‐induced eosinophilic airway inflammation by increasing IL‐33 expression and activating ILC2s
K Saito, K Orimo, T Kubo, M Tamari, A Yamada… - Allergy, 2023 - Wiley Online Library
Introduction Epidemiological studies demonstrated that cleaning work and frequent use of
cleaning products are risk factors for asthma. Laundry detergents have been reported to …
cleaning products are risk factors for asthma. Laundry detergents have been reported to …
Decoding the genetic and epigenetic basis of asthma
Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
[HTML][HTML] Airway remodeling heterogeneity in asthma and its relationship to disease outcomes
A Hsieh, N Assadinia, TL Hackett - Frontiers in physiology, 2023 - frontiersin.org
Asthma affects an estimated 262 million people worldwide and caused over 461,000 deaths
in 2019. The disease is characterized by chronic airway inflammation, reversible …
in 2019. The disease is characterized by chronic airway inflammation, reversible …
Protease allergens as initiators–regulators of allergic inflammation
Tremendous progress in the last few years has been made to explain how seemingly
harmless environmental proteins from different origins can induce potent Th2‐biased …
harmless environmental proteins from different origins can induce potent Th2‐biased …
[HTML][HTML] IL-4 and IL-13, not eosinophils, drive type 2 airway inflammation, remodeling and lung function decline
Abstract Rationale Type 2 (T2) asthma is characterized by airflow limitations and elevated
levels of blood and sputum eosinophils, fractional exhaled nitric oxide, IgE, and periostin …
levels of blood and sputum eosinophils, fractional exhaled nitric oxide, IgE, and periostin …
TSLP shapes the pathogenic responses of memory CD4+ T cells in eosinophilic esophagitis
Y Rochman, M Kotliar, N Ben-Baruch Morgenstern… - Science …, 2023 - science.org
The cytokine thymic stromal lymphopoietin (TSLP) mediates type 2 immune responses, and
treatments that interfere with TSLP activity are in clinical use for asthma. Here, we …
treatments that interfere with TSLP activity are in clinical use for asthma. Here, we …
The understanding of asthma pathogenesis in the era of precision medicine
N Hizawa - Allergology International, 2023 - jstage.jst.go.jp
abstract Asthma is a syndrome with extremely diverse clinical phenotypes in which the
onset, severity, and response to treatment are defined by the complex interplay of many …
onset, severity, and response to treatment are defined by the complex interplay of many …
[HTML][HTML] Knowledge mapping and research trends of IL-33 from 2004 to 2022: a bibliometric analysis
J Jin, Y Wan, Q Shu, J Liu, D Lai - Frontiers in Immunology, 2023 - frontiersin.org
Background IL-33 has been studied widely but its comprehensive and systematic
bibliometric analysis is yet available. The present study is to summarize the research …
bibliometric analysis is yet available. The present study is to summarize the research …