The role of trace elements and minerals in osteoporosis: a review of epidemiological and laboratory findings

AV Skalny, M Aschner, EV Silina, VA Stupin… - Biomolecules, 2023 - mdpi.com
The objective of the present study was to review recent epidemiological and clinical data on
the association between selected minerals and trace elements and osteoporosis, as well as …

Functional micro-RNA drugs acting as a fate manipulator in the regulation of osteoblastic death

Z Cai, F Liu, Y Li, L Bai, M Feng, S Li, W Ma, S Shi - Nanoscale, 2023 - pubs.rsc.org
Bone loss is prevalent in clinical pathological phenomena such as osteoporosis, which is
characterized by decreased osteoblast function and number, increased osteoclast activity …

DNAzyme nanoconstruct-integrated autonomously-adaptive coatings enhance titanium-implant osteointegration by cooperative angiogenesis and vessel remodeling

M Chen, M Li, X Ren, F Zhou, Y Li, L Tan, Z Luo… - ACS …, 2023 - ACS Publications
Orthopedic implants have a high failure rate due to insufficient interfacial osseointegration,
especially under osteoporotic conditions. Type H vessels are CD31+ EMCN+ capillaries …

[HTML][HTML] S-sulfhydration of SIRT3 combats BMSC senescence and ameliorates osteoporosis via stabilizing heterochromatic and mitochondrial homeostasis

F Liu, L Yuan, L Li, J Yang, J Liu, Y Chen… - Pharmacological …, 2023 - Elsevier
Senescence of bone marrow mesenchymal stem cells (BMSCs) is one of the leading causes
of osteoporosis. SIRT3, an essential NAD-dependent histone deacetylase, is highly …

Purine metabolism-related genes and immunization in thyroid eye disease were validated using bioinformatics and machine learning

Z Wu, Y Gao, L Cao, Q Peng, X Yao - Scientific Reports, 2023 - nature.com
Thyroid eye disease (TED), an autoimmune inflammatory disorder affecting the orbit,
exhibits a range of clinical manifestations. While the disease presentation can vary, cases …

Computational Study of the Interaction of C12P12 and C12N12 Nanocages with Alendronate Drug Molecule

L Hitler, JF Eze, AD Nwagu, HO Edet… - …, 2023 - Wiley Online Library
The utilization of nanomaterials as efficient delivery systems to specific metabolic sites is
essential for harnessing the utmost therapeutic potency of drugs leading to a tremendous …

Emphatic information on bone mineral loss using quantitative ultrasound sonometer for expeditious prediction of osteoporosis

K Ramaraj, PR Murugan, G Amiya, V Govindaraj… - Scientific reports, 2023 - nature.com
Osteoporosis (OP) and osteoarthritis (OA) are skeletal disorders characterized by a
reduction in bone density and quality, resulting in increased fragility and susceptibility to …

Characterizing bone phenotypes related to skeletal fragility using advanced medical imaging

DE Whittier, MSAM Bevers, PPMM Geusens… - Current Osteoporosis …, 2023 - Springer
Abstract Purpose of Review Summarize the recent literature that investigates how advanced
medical imaging has contributed to our understanding of skeletal phenotypes and fracture …

Effects of isoflavone and probiotic intake on calcium transport and bone metabolism biomarkers in female rats

IA Harahap, M Kuligowski, M Schmidt… - Food Science & …, 2023 - Wiley Online Library
Calcium is essential for maintaining bone health as it contributes to bone formation,
remodeling, strength, and density. This study investigated the effect of isoflavones and …

Bioinformatics and machine learning were used to validate glutamine metabolism-related genes and immunotherapy in osteoporosis patients

L Wang, C Deng, Z Wu, K Zhu, Z Yang - Journal of Orthopaedic Surgery …, 2023 - Springer
Background Osteoporosis (OP), often referred to as the “silent disease of the twenty-first
century,” poses a significant public health concern due to its severity, chronic nature, and …