[HTML][HTML] European LeukemiaNet laboratory recommendations for the diagnosis and management of chronic myeloid leukemia
NCP Cross, T Ernst, S Branford, JM Cayuela… - Leukemia, 2023 - nature.com
From the laboratory perspective, effective management of patients with chronic myeloid
leukemia (CML) requires accurate diagnosis, assessment of prognostic markers, sequential …
leukemia (CML) requires accurate diagnosis, assessment of prognostic markers, sequential …
Assessment of acute myeloid leukemia molecular measurable residual disease testing in an interlaboratory study
Abstract The European LeukaemiaNet (ELN) measurable residual disease (MRD) working
group has published consensus guidelines to standardize molecular genetic MRD testing of …
group has published consensus guidelines to standardize molecular genetic MRD testing of …
Committed change of real-time quantitative PCR to droplet digital PCR for monitoring BCR::ABL1 transcripts in tyrosine kinase inhibitor treated CML
A Kongruang, N Limsuwanachot, S Magmuang… - …, 2023 - Taylor & Francis
Objectives We performed a feasibility study of an FDA-approved commercial ddPCR assay
to measure BCR:: ABL1 in CML patients treated using TKI therapy. Methods Assay …
to measure BCR:: ABL1 in CML patients treated using TKI therapy. Methods Assay …
Children with chronic myeloid leukaemia treated with front-line imatinib have a slower molecular response and comparable survival compared with adults: a …
HC Liu, MC Kuo, KH Wu, TY Chen, JS Chen… - British Journal of …, 2023 - nature.com
Background The direct comparison of molecular responses of front-line imatinib (IM)
monitored at the same laboratory between children and adults with chronic phase (CP) of …
monitored at the same laboratory between children and adults with chronic phase (CP) of …
[HTML][HTML] Reverse Transcription Can Critically Impact the Diagnostic Outcome of BCR::ABL1 Quantitative Real-Time RT-PCR
B Spiess, H Kleiner, I Tarnopolscaia, N Naumann… - Cancers, 2023 - mdpi.com
Simple Summary Reverse transcriptases (RT) play a crucial role in BCR:: ABL1 fusion
transcript monitoring of chronic myeloid leukemia (CML). RT enzyme and reaction …
transcript monitoring of chronic myeloid leukemia (CML). RT enzyme and reaction …
[HTML][HTML] Development and validation of sensitive BCR::ABL1 fusion gene quantitation using next-generation sequencing
H Lee, J Seo, S Shin, ST Lee, JR Choi - Cancer Cell International, 2023 - Springer
Background BCR:: ABL1 fusion has significant prognostic value and is screened for chronic
myeloid leukemia (CML) disease monitoring as a part of routine molecular testing. To …
myeloid leukemia (CML) disease monitoring as a part of routine molecular testing. To …