Single cell epigenomic and transcriptomic analysis uncovers potential transcription factors regulating mitotic/meiotic switch

FL Zhang, YQ Feng, JY Wang, KX Zhu, L Wang… - Cell Death & …, 2023 - nature.com
In order to reveal the complex mechanism governing the mitotic/meiotic switch in female
germ cells at epigenomic and genomic levels, we examined the chromatin accessibility …

Current understanding of the genomic abnormities in premature ovarian failure: chance for early diagnosis and management

X Yang, L Yang - Frontiers in Medicine, 2023 - frontiersin.org
Premature ovarian failure (POF) is an insidious cause of female infertility and a devastating
condition for women. POF also has a strong familial and heterogeneous genetic …

Discovery of Oogenesis Biomarkers from Mouse Oocytes Using a Single-Cell Proteomics Approach

Q Li, L Mu, X Yang, G Wang, J Liang… - Journal of Proteome …, 2023 - ACS Publications
We established an efficient and simplified single-cell proteomics (ES–SCP) workflow to
realize proteomics profiling at the single-oocyte level. With the ES–SCP workflow, we …

[HTML][HTML] Local regulation of antral follicle development and ovulation in monovulatory species

FP Moraes, D Missio, J Lazzari, MT Rovani… - Animal …, 2023 - SciELO Brasil
The identification of mutations in the genes encoding bone morphogenetic protein 15
(BMP15) and growth and differentiation factor 9 (GDF9) associated with phenotypes of …

[HTML][HTML] Application of specific ELISAs for BMP15 and GDF9 to cumulus cell extracts from infertile women

AE Krysta-Matter, AH Riepsamen, S Lien… - Molecular and Cellular …, 2023 - Elsevier
Abstract Bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9)
are oocyte-specific paracrine factors which regulate ovarian cumulus cell (CC) functions …

Decreased GDF9 and BMP15 in follicle fluid and granulosa cells and outcomes of IVF-ET among young patients with low prognosis

T Huang, F Chen, Y Zhang, S Chen, F Long… - Journal of Assisted …, 2023 - Springer
Purpose To analyze the level of growth differentiation factor 9 (GDF9) and bone
morphogenetic protein 15 (BMP15) in follicle fluid (FF) and granulosa cells (GCs) derived …

Oocyte-secreted serum biomarkers GDF9 and BMP15 in women with endometriosis

A Shamsa, RB Gilchrist, DM Robertson… - Reproductive …, 2023 - Springer
Oocyte-secreted growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15
(BMP15) are critical paracrine regulators of female fertility. Recent studies demonstrated that …

Screening for causative mutations in ovine BMPR1B and BMP15 genes and their homologous fragments in human

P Zamani, F Rabiei, E Hadiei, R Abdoli… - Journal of Assisted …, 2023 - Springer
Abstract Purpose The BMPR1B and BMP15 genes are well known for their considerable
associations with prolificacy in sheep. These genes may also affect fertility or prolificacy in …

[HTML][HTML] Effects of obesity on the serum BMP15, GDF9, and kisspeptin concentrations in women of reproductive age

FB Arıkan, N Sagsoz - Journal of Medical Biochemistry, 2023 - ncbi.nlm.nih.gov
Background As BMP15, GDF9, and kisspeptin all play critical roles in folliculogenesis and
fertilization, investigating the possible relationship between obesity and these three factors …

Genetic polymorphism of the BMP15 gene in West African sheep (Fulani) breed in Sudan

KH Elshareef, HH Musa, SY Adam, JS Fedailb… - Applied Veterinary …, 2023 - malque.pub
Genetic polymorphism studies in domestic animals aim at assessing genetic variations
within and across breeds mainly for preservation purposes. The bone morphogenetic …