[HTML][HTML] Research advances in peptide‒drug conjugates
L Gong, H Zhao, Y Liu, H Wu, C Liu, S Chang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Peptide‒drug conjugates (PDCs) are drug delivery systems consisting of a drug covalently
coupled to a multifunctional peptide via a cleavable linker. As an emerging prodrug strategy …
coupled to a multifunctional peptide via a cleavable linker. As an emerging prodrug strategy …
Therapeutic supramolecular polymers: Designs and applications
The self-assembly of low-molecular-weight building motifs into supramolecular polymers
has unlocked a new realm of materials with distinct properties and tremendous potential for …
has unlocked a new realm of materials with distinct properties and tremendous potential for …
Application of molecular dynamics simulation in self-assembled cancer nanomedicine
X Xu, A Liu, S Liu, Y Ma, X Zhang, M Zhang… - Biomaterials …, 2023 - spj.science.org
Self-assembled nanomedicine holds great potential in cancer theragnostic. The structures
and dynamics of nanomedicine can be affected by a variety of non-covalent interactions, so …
and dynamics of nanomedicine can be affected by a variety of non-covalent interactions, so …
Drug Self‐Delivery Systems: Molecule Design, Construction Strategy, and Biological Application
C Liu, C Liu, Y Bai, J Wang… - Advanced Healthcare …, 2023 - Wiley Online Library
Drug self‐delivery systems (DSDSs) offer new ways to create novel drug delivery systems
(DDSs). In typical DSDSs, therapeutic reagents are not considered passive cargos but active …
(DDSs). In typical DSDSs, therapeutic reagents are not considered passive cargos but active …
Stimulus‐Responsive Nano‐Prodrug Strategies for Cancer Therapy: A Focus on Camptothecin Delivery
B Chu, H Deng, T Niu, Y Qu, Z Qian - Small Methods, 2023 - Wiley Online Library
Camptothecin (CPT) is a highly cytotoxic molecule with excellent antitumor activity against
various cancers. However, its clinical application is severely limited by poor water solubility …
various cancers. However, its clinical application is severely limited by poor water solubility …
Reactive oxygen species‐responsive polymeric prodrug nanoparticles for selective and effective treatment of inflammatory diseases
It is challenging to manage inflammatory diseases using traditional anti‐inflammatory drugs
due to their limited efficacy and systemic side effects, which are a result of their lack of …
due to their limited efficacy and systemic side effects, which are a result of their lack of …
Core–shell type lipidic and polymeric nanocapsules: the transformative multifaceted delivery systems
Amongst the several nano-drug delivery systems, lipid or polymer-based core–shell
nanocapsules (NCs) have garnered much attention of researchers owing to its …
nanocapsules (NCs) have garnered much attention of researchers owing to its …
NIR-responsive carrier-free nanoparticles based on berberine hydrochloride and indocyanine green for synergistic antibacterial therapy and promoting infected …
Y Duan, P Xu, P Ge, L Chen, Y Chen… - Regenerative …, 2023 - academic.oup.com
Bacterial infections cause severe health conditions, resulting in a significant economic
burden for the public health system. Although natural phytochemicals are considered …
burden for the public health system. Although natural phytochemicals are considered …
Self-Assembled Nanobiomaterials for Combination Immunotherapy
J Paul V, P Sharma, A Shanavas - ACS Applied Bio Materials, 2023 - ACS Publications
Nanotechnological interventions for cancer immunotherapy are a rapidly evolving paradigm
with immense potential. Self-assembled nanobiomaterials present safer alternatives to their …
with immense potential. Self-assembled nanobiomaterials present safer alternatives to their …
Tumor permeable self-delivery nanodrug targeting mitochondria for enhanced chemotherapy
G Yuan, Y Zhang, S Shao, Z Zhou, J Tang… - Journal of Controlled …, 2023 - Elsevier
Drug self-delivery systems (DSDSs) have been extensively exploited to enhance drug
loading capacity and avoid excipient-related toxicity issues. However, deficient tumor …
loading capacity and avoid excipient-related toxicity issues. However, deficient tumor …