The harmful use of alcohol is responsible for 5.1% of the global burden of disease, and the
early detection of alcohol problems may prevent its development and progression …

With urinary proteomics profiling (UPP) as exemplary omics technology, this review
describes a workflow for the analysis of omics data in large study populations. The proposed …

Endogenous biomolecules in cells are the basis of all life activities. Directly visualizing the
structural characteristics and dynamic behaviors of cellular biomolecules is significant for …

Peptides carry important functions in normal physiological and pathophysiological
processes and can serve as clinically useful biomarkers. Given the ability to diffuse …

Systemic sclerosis (SSc) is a rheumatic disease characterised by vasculopathy,
inflammation and fibrosis. Its aetiopathogenesis is still unknown, and the …

Simple Summary Prostate cancer is the most frequent cancer type and one of the leading
causes of death in men globally. Multiple biomarkers analyzed in urine have been proposed …

Brain metastases (BM) are a common and devastating manifestation of breast cancer (BC).
BM are particularly frequent in the HER2-positive and triple-negative breast cancer …

Extracellular vesicles (EVs) are used by living cells for the purpose of biological information
trafficking from parental-to-recipient cells and vice versa. This back-and-forth communication …

Introduction The identification of patients with chronic kidney disease (CKD) at risk of
progressing to kidney failure (KF) is important for clinical decision-making. In this study we …

Myasthenia Gravis (MG) is an autoimmune disease associated with severe neuromuscular
weakness. Diagnostic confirmation of MG is typically delayed and secured in about 85% and …