The genomic simplicity of differentiated cancers derived from thyroid follicular cells offers
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …

The treatment of advanced, radioiodine refractory, differentiated thyroid cancers (RR-DTCs)
has undergone major advancements in the last decade, causing a paradigm shift in the …

Context Comprehensive genomic analysis of thyroid nodules for multiple classes of
molecular alterations detected in a large series of fine needle aspiration (FNA) samples has …

The 5th edition of the Classification of Endocrine and Neuroendocrine Tumors has been
released by the World Health Organization (WHO). This timely publication integrates several …

Mitochondrial DNA (mtDNA) is as a double-stranded molecule existing in hundreds to
thousands copies in cells depending on cell metabolism and exposure to endogenous …

Background: Very little was known about the molecular pathogenesis of thyroid cancer until
the late 1980s. As part of the Centennial celebration of the American Thyroid Association …

Thyroid nodules are quite common, and the determination of a nodule of concern is
complex, involving serum testing, radiology and, in some cases, pathological evaluation. For …

Whole chromosome instability with near-whole genome haploidization (GH) and
subsequent endoreduplication is considered a main genomic driver in the tumorigenesis of …

Background Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer
(TC). Several genomic and transcriptomic studies explored the molecular landscape of …

Abstract “Inflammatory rhabdomyoblastic tumor”(IRMT) is a recently coined name for a
distinctive soft tissue neoplasm characterized by slow growth, a dense histiocytic infiltrate …