[HTML][HTML] Thrombosis in the pathogenesis of abdominal aortic aneurysm

J Bontekoe, J Matsumura, B Liu - JVS-Vascular Science, 2023 - Elsevier
Abstract Background Abdominal aortic aneurysms (AAAs) are a relatively common vascular
pathology of the elderly with high morbidity potential. Irreversible degeneration of the aortic …

Investigation of a UPR-Related Gene Signature Identifies the Pro-Fibrotic Effects of Thrombospondin-1 by Activating CD47/ROS/Endoplasmic Reticulum Stress …

JH Zhan, J Wei, L Liu, YT Xu, H Ji, CN Wang, YJ Liu… - Antioxidants, 2023 - mdpi.com
Unfolded protein response (UPR) signaling and endoplasmic reticulum (ER) stress have
been linked to pulmonary fibrosis. However, the relationship between UPR status and …

ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice

Z Gong, J Huang, D Wang, S Yang, Z Ma, Y Fu… - Journal of Molecular …, 2023 - Springer
Thoracic aortic aneurysm and dissection (TAAD) is a life-threatening cardiovascular disease
with severe extracellular matrix (ECM) remodeling that lacks efficient early stage diagnosis …

Animal Models and Pathogenesis of Thoracic Aortic Aneurysm

Y Wang, IS Panicker, J Anesi, O Sargisson… - 2023 - preprints.org
Thoracic aortic aneurysm (TAA) has a prevalence of 0.16%-0.34% and an incidence of 7.6
per 100,000 person-years, accounting for 1%-2% of all deaths in Western countries …