Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Cellular and molecular pathophysiology of traumatic brain injury: what have we learned so far?

MAM Freire, GS Rocha, LO Bittencourt, D Falcao… - Biology, 2023 - mdpi.com
Simple Summary Traumatic brain injury (TBI) is a catastrophic event to the health and life of
its sufferers, and it also affects their relatives. In addition to the underlying complications of …

[HTML][HTML] A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury

Z Li, T Zhao, J Ding, H Gu, Q Wang, Y Wang, D Zhang… - Bioactive materials, 2023 - Elsevier
Spinal cord injury (SCI) is an overwhelming and incurable disabling event accompanied by
complicated inflammation-related pathological processes, such as excessive reactive …

The burden of Parkinson's disease in the Middle East and North Africa region, 1990–2019: results from the global burden of disease study 2019

S Safiri, M Noori, SA Nejadghaderi, SE Mousavi… - BMC Public Health, 2023 - Springer
Background Parkinson's disease (PD) remains a common disabling progressive
neurodegenerative disorder. We aimed to report the prevalence, death and disability …

Recent advances in the role of miRNAs in post-traumatic stress disorder and traumatic brain injury

Z Zhu, X Huang, M Du, C Wu, J Fu, W Tan, B Wu… - Molecular …, 2023 - nature.com
Post-traumatic stress disorder (PTSD) is usually considered a psychiatric disorder upon
emotional trauma. However, with the rising number of conflicts and traffic accidents around …

Incidence and predictors of mortality among traumatic brain injury patients admitted to Amhara region Comprehensive Specialized Hospitals, northwest Ethiopia, 2022

TA Demlie, MT Alemu, MA Messelu, F Wagnew… - BMC emergency …, 2023 - Springer
Introduction Traumatic brain injury is a substantial cause of mortality and morbidity with a
higher burden in low and middle-income countries due to healthcare systems that are …

Management of traumatic brain injury in the non‐neurosurgical intensive care unit: a narrative review of current evidence

MD Wiles, M Braganza, H Edwards, E Krause… - …, 2023 - Wiley Online Library
Each year, approximately 70 million people suffer traumatic brain injury, which has a
significant physical, psychosocial and economic impact for patients and their families. It is …

Cannabidiol's neuroprotective properties and potential treatment of traumatic brain injuries

MM Aychman, DL Goldman, JS Kaplan - Frontiers in neurology, 2023 - frontiersin.org
Cannabidiol (CBD) has numerous pharmacological targets that initiate anti-inflammatory,
antioxidative, and antiepileptic properties. These neuroprotective benefits have generated …

Incidence, prevalence and disability of spinal cord injury in China from 1990 to 2019: a systematic analysis of the Global Burden of Disease Study 2019

S Hu, P Wang, Y Dong, F Li - European Spine Journal, 2023 - Springer
Purpose We aimed to estimate the incidence, prevalence and years lived with disability
(YLDs) of spinal cord injury (SCI) in China in 2019 and temporal trends from 1990 to 2019 …

[HTML][HTML] Generation of direct current electrical fields as regenerative therapy for spinal cord injury: A review

L Matter, B Harland, B Raos, D Svirskis… - APL bioengineering, 2023 - pubs.aip.org
Electrical stimulation (ES) shows promise as a therapy to promote recovery and
regeneration after spinal cord injury. ES therapy establishes beneficial electric fields (EFs) …