Comprehensive review on natural pharmacophore tethered 1, 2, 3‐triazoles as active pharmaceuticals

A Rammohan, BC Venkatesh… - Chemical Biology & …, 2023 - Wiley Online Library
Abstract The privileged 1, 2, 3‐triazole scaffold is drawing researcher's attention due to its
widespread applications in diverse fields such as drug discovery (eg, carboxyamidotriazole) …

A concise review of multicomponent reactions using novel heterogeneous catalysts under microwave irradiation

T Damera, R Pagadala, S Rana, SB Jonnalagadda - Catalysts, 2023 - mdpi.com
Multi-component reactions for the construction of heterocycles have been fascinated by
microwave energy as an alternative technique of heating, owing to the advantages over …

Synthesis, antimicrobial activity and molecular docking of novel benzimidazole conjugated 1, 2, 3-triazole analogues

V Mallikanti, V Thumma, R Matta, KR Valluru… - Chemical Data …, 2023 - Elsevier
A library of novel benzimidazole based 1, 2, 3-triazoles were synthesized by a series of
reactions containing Suzuki coupling, cyclization and microwave assisted copper catalyzed …

Decarboxylative triazolation enables direct construction of triazoles from carboxylic acids

HT Dang, VD Nguyen, GC Haug, HD Arman… - JACS Au, 2023 - ACS Publications
Triazoles have major roles in chemistry, medicine, and materials science, as centrally
important heterocyclic motifs and bioisosteric replacements for amides, carboxylic acids, and …

Coumarin triazoles as potential antimicrobial agents

SA Patil, AR Nesaragi, RR Rodríguez-Berrios… - Antibiotics, 2023 - mdpi.com
Currently, in hospitals and community health centers, microbial infections are highly
common diseases and are a leading cause of death worldwide. Antibiotics are generally …

Recent advancements in triazole-based click chemistry in cancer drug discovery and development

A Kumar, AK Yadav, V Mishra, D Kumar - SynOpen, 2023 - thieme-connect.com
Thieme E-Journals - SynOpen / Full Text DE EN Home Products Journals Books Book Series
Service Library Service Help Contact Portal SynOpen Full-text search Full-text search Author …

[HTML][HTML] 1, 5-disubstituted-1, 2, 3-triazoles counteract mitochondrial dysfunction acting on F1FO-ATPase in models of cardiovascular diseases

C Algieri, C Bernardini, S Marchi, M Forte… - Pharmacological …, 2023 - Elsevier
The compromised viability and function of cardiovascular cells are rescued by small
molecules of triazole derivatives (Tzs), identified as 3a and 3b, by preventing mitochondrial …

A comprehensive review on triazole based conjugates as acetylcholinesterase inhibitors: Design strategies, synthesis, biological activity, structure activity …

HK Gulati, N Kumar, A Sharma, A Khanna… - Journal of Molecular …, 2023 - Elsevier
Significant advancements have been made in development of Acetylcholinesterase
inhibitors as Anti-Alzheimer drugs. Triazoles, a 5-membered heterocyclic nucleus containing …

Phytochemical Constituents of Adansonia digitata L. (Baobab) Fruit Pulp from Tekeze Valley, Tigrai, Ethiopia

AA Wasihun, DB Sbhatu, GG Berhe… - … Journal of Analytical …, 2023 - Wiley Online Library
Baobab (Adansonia digitata L) is a large tree species growing in semiarid and arid lowlands
of Ethiopia and other places. The plant is valued by natives for its contributions as a cash …

[HTML][HTML] Steroid-triazole conjugates: A brief overview of synthesis and their application as anticancer agents

DS Agarwal, R Sakhuja, RM Beteck, LJ Legoabe - Steroids, 2023 - Elsevier
Steroids are biomolecules that play pivotal roles in various physiological and drug discovery
processes. Abundant research has been fuelled towards steroid-heterocycles conjugates …