Natural antioxidants from some fruits, seeds, foods, natural products, and associated health benefits: An update

MM Rahaman, R Hossain… - Food science & …, 2023 - Wiley Online Library
Antioxidants are compounds that inhibit the oxidation of other molecules and protect the
body from the effects of free radicals, produced either by normal cell metabolism or as an …

[HTML][HTML] Camellia sinensis: insights on its molecular mechanisms of action towards nutraceutical, anticancer potential and other therapeutic applications

P Chaudhary, D Mitra, PKD Mohapatra… - Arabian Journal of …, 2023 - Elsevier
The Camellia sinensis plant provides a wide diversity of black, green, oolong, yellow, brick
dark, and white tea. Tea is one of the majorly used beverages across the globe, succeeds …

[HTML][HTML] Potential of cucurbitacin as an anticancer drug

Y Li, Y Li, Y Yao, H Li, C Gao, C Sun… - Biomedicine & …, 2023 - Elsevier
Abstract In Chinese medicine, the Cucurbitaceae family contains many compounds known
as cucurbitacins, which have been categorized into 12 classes ranging from A to T and more …

[HTML][HTML] Key oncologic pathways inhibited by Erinacine A: a perspective for its development as an anticancer molecule

P Prasher, M Sharma, AK Sharma, J Sharifi-Rad… - Biomedicine & …, 2023 - Elsevier
In the modern era, cancer can be controlled by chemotherapy treatment, and in many
situations a stable disease is obtained. The significant clinical success and subsequent …

Recent Advances in the Application of Cucurbitacins as Anticancer Agents

B Zieniuk, M Pawełkowicz - Metabolites, 2023 - mdpi.com
Cucurbitacins are tetracyclic triterpenoid secondary metabolites, widely distributed in the
Cucurbitaceae family. These bitter-tasting compounds act primarily as defense mechanisms …

Phytochemicals target multiple metabolic pathways in cancer

O Shuvalov, Y Kirdeeva, A Daks, O Fedorova… - Antioxidants, 2023 - mdpi.com
Cancer metabolic reprogramming is a complex process that provides malignant cells with
selective advantages to grow and propagate in the hostile environment created by the …

A comprehensive review on traditional uses, phytochemistry and pharmacological properties of Paeoniaemodi Wall. ex Royle: current landscape and future …

N Zahra, J Iqbal, M Arif, BA Abbasi, H Sher, AF Nawaz… - Chinese Medicine, 2023 - Springer
Abstract Paeonia emodi Wall. ex Royle is commonly known as Himalayan paeony has great
importance as a food and medicine. The practice of Paeonia emodi Wall. ex Royle is very …

Cucurbitacin E exerts anti-proliferative activity via promoting p62-dependent apoptosis in human non-small-cell lung cancer A549 cells

HL Hsu, BJ Lin, YC Lin, CC Tu, NL Nguyen… - Current Issues in …, 2023 - mdpi.com
EGFR tyrosine kinase inhibitors (TKIs) are the first-line treatment for advanced EGFR-
mutated non-small-cell lung cancer (NSCLC). However, NSCLC patients with wild-type …

Cucurbitacin B protects against myocardial ischemia-reperfusion injury through activating JAK2/STAT3 signaling pathway

C Chen, Y Chen, M Xu, L Chen, Z Sun… - Cellular and …, 2023 - mail.cellmolbiol.org
Cucurbitacin B, a tetracyclic triterpenoid compound extracted from various plants, has been
proven to exert a vital role in various diseases. However, the effect of cucurbitacin B on …

Cucurbitacin-B instigates intrinsic apoptosis and modulates Notch signaling in androgen-dependent prostate cancer LNCaP cells

A Alafnan, NE Khalifa, T Hussain… - Frontiers in …, 2023 - frontiersin.org
Introduction: Among numerous triterpenoids of the Cucurbitaceae family, Cucurbitacin-B
(Cur-B) is being explored for its pharmacological attributes. Reports from previous studies …