TIMER is a Siamese neural network-based framework for identifying both general and species-specific bacterial promoters

Y Zhu, F Li, X Guo, X Wang, LJM Coin… - Briefings in …, 2023 - academic.oup.com
Background Promoters are DNA regions that initiate the transcription of specific genes near
the transcription start sites. In bacteria, promoters are recognized by RNA polymerases and …

Sigma factors of RNA polymerase in the pathogenic spirochaete Leptospira interrogans, the causative agent of leptospirosis

S KędzierskaMieszkowska - The FASEB Journal, 2023 - Wiley Online Library
The aim of this review is to summarize the current knowledge on the role of σ factors in a
highly invasive spirochaete Leptospira interrogans responsible for leptospirosis that affects …

Immunoreactivity of a Putative ECF σ Factor, LIC_10559, from Leptospira interrogans with Sera from Leptospira-Infected Animals

S Kędzierska-Mieszkowska, Z Arent - Pathogens, 2023 - mdpi.com
L. interrogans belongs to highly invasive spirochaetes causing leptospirosis in mammals,
including humans. During infection, this pathogen is exposed to various stressors, and …

Leptospira transcriptome sequencing using long-read technology reveals unannotated transcripts and potential polyadenylation of RNA molecules

R Xu, D Prakoso, LCM Salvador… - Microbiology Spectrum, 2023 - Am Soc Microbiol
Leptospirosis, caused by the spirochete bacteria Leptospira, is an emerging zoonosis that
causes life-threatening disease in humans and animals. However, a comprehensive …

Crystal structure of Leptospira LSS_01692 reveals a dimeric structure and induces inflammatory responses through Tolllike receptor 2dependent NF螃B and MAPK …

SH Hsu, CT Wu, YJ Sun, MY Chang, C Li… - The FEBS …, 2023 - Wiley Online Library
Leptospirosis is a commonly overlooked zoonotic disease that occurs in tropical and
subtropical regions. Recent studies have divided the Leptospira spp. into three groups …

Transcription start site mapping and small RNA profiling of Leptospira biflexa serovar Patoc

HL Cheah, SA Ahmed, TH Tang - World Journal of Microbiology and …, 2023 - Springer
Leptospirosis is an emerging zoonotic disease caused by bacterial species of the genus
Leptospira. However, the regulatory mechanisms and pathways underlying the adaptation of …

Biocomputational Identification of sRNAs in Leptospira interrogans Serovar Lai

XY Tan, M Citartan, SV Chinni, SA Ahmed… - Indian journal of …, 2023 - Springer
Regulatory small RNAs (sRNA) are RNA transcripts that are not translated into proteins but
act as functional RNAs. Pathogenic Leptospira cause an epidemic spirochaetal zoonosis …

[PDF][PDF] Immunoreactivity of a Putative ECF σ Factor, LIC_10559, from Leptospira interrogans with Sera from Leptospira-Infected Animals. Pathogens 2023, 12, 512

S Kedzierska-Mieszkowska, Z Arent - 2023 - academia.edu
L. interrogans belongs to highly invasive spirochaetes causing leptospirosis in mammals,
including humans. During infection, this pathogen is exposed to various stressors, and …

Using Multi-Omics Data to Study Leptospira sp. Across Multiple Biological Scales

R Xu - 2023 - search.proquest.com
Leptospirosis, caused by the bacterial spirochete Leptospira, is a tropical neglected disease
infecting many mammalian hosts and leading to a large amount of morbidity and mortality in …